Cochrane · systematic review · CD014906
Protein restriction for diabetic kidney disease
Jiang, S, Fang, J, Li, W · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 20%Very low 2 · 40%Low 2 · 40%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Low protein diet versus usual or unrestricted protein diet for adults with diabetic kidney disease
Population: adults with DKD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death (any cause) Low protein diet vs usual or unrestricted protein diet | RR 0.38 [0.1, 1.44] | 5 studies · 358 participants | Low Downgraded: imprecision |
Kidney failure Low protein diet vs usual or unrestricted protein diet | RR 1.16 [0.38, 3.59] | 4 studies · 287 participants | Low Downgraded: imprecision |
Change in GFR Low protein diet vs usual or unrestricted protein diet | no estimate extracted | 7 studies · 367 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Change in 24‐hour urinary protein excretion Low protein diet vs usual or unrestricted protein diet | no estimate extracted | 1 study · 80 participants | Very low Downgraded: risk of bias, imprecision |
Malnutrition Low protein diet vs usual or unrestricted protein diet | no estimate extracted | 7 studies · 471 participants | Ungraded |