Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

516 questions · 950 findings · 74 reviews · Dental caries

No studies found 35 · 3.7%GRADE not reported 831 · 87.5%Very low 38 · 4%Low 26 · 2.7%Moderate 13 · 1.4%High 7 · 0.7%

Pre-operative caries fillings or crowns vs Intact teeth

Pulp necrosis · Vital teeth

One study reported a 13% incidence in teeth with pre-operative caries fillings or crowns.

2 findings from 1 review

Pre-operative bone level < 35% vs Pre-operative bone level ≥ 35%

Periapical pathosis incidence · Vital teeth

One study reported a 1.4% incidence with bone level < 35%.

2 findings from 1 review

Eugenol-based temporary cement vs Eugenol-free temporary cement

Pulp necrosis · Vital teeth

The pooled incidence with eugenol-based temporary cement was 3.34%.

2 findings from 1 review

Gum chewing (sugar-free) vs No chewing gum

Self-reported thirst · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

Gum chewing reduced self-reported thirst in most studies (6 of 7 positive, 1 no effect); not meta-analyzed.

1 finding from 1 review

Indirect restorations (crowns, fixed partial dentures, inlays/onlays/veneers) vs None (single-group incidence)

Periapical pathosis · Vital teeth restored with indirect restorations

Periapical pathosis incidence among follow-up >5-10 years was 3.88% (subgroup analysis; not GRADE-rated).

6 findings from 1 review
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Gum chewing (sugar-free) vs Within-subject before/after comparison of soft gum vs hard gum (no no-gum control)

Oral mucosal moisture · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

One small study found that chewing hard (but not soft) gum increased oral mucosal moisture.

1 finding from 1 review

Polyether impression material vs Polyvinyl siloxane impression material

Pulp necrosis · Vital teeth

The pooled incidence with polyether impression material was 4.02%.

2 findings from 1 review

Pulp-status assessment method

Pulp necrosis · Vital teeth

The pooled incidence with radiographic assessment was 4.95%.

2 findings from 1 review

Gum chewing (sugar-free) vs No chewing gum

Dry mouth (xerostomia) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

Gum chewing was linked with improved self-reported xerostomia / dry mouth in most studies (12 of 17 positive, 5 no effect); heterogeneous instruments precluded meta-analysis.

1 finding from 1 review

Preterm birth (<37 weeks gestation) vs Full-term birth (37 weeks or more gestation)

Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)

In children aged 3 years or younger, preterm birth was not associated with early childhood caries (OR 0.90, 95% CI 0.59 to 1.37); certainty not graded.

2 findings from 1 review