Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Prophylactic platelet transfusion prior to surgery vs alternative treatment

Serious adverse events (transfusion‐related adverse effects within 24 hours of the transfusion) · people with a low platelet count

It is very uncertain whether prophylactic platelet transfusion prior to surgery changes serious adverse events (transfusion‐related adverse effects within… compared with alternative treatments (very low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) vs the Linton procedure

The proportion of pressure ulcers healed · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) changes proportion of ulcers healed at 24 months compared with the Linton procedure (very low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in unmedicated IOP24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in unmedicated IOP24 months (medium‐term) compared with phacoemulsification alone (high certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in daily IOP‐lowering medicationsat 24 months… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants experiencing postoperative complicationsover 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in proportion of participants experiencing postoperative… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Botulinum toxin vs surgery

Proportion of participants requiring additional surgery(ies) at 6 or 12 months · adults and children with strabismus

It is very uncertain whether botulinum toxin changes proportion of participants requiring additional surgery(ies) at 6 or… compared with surgery (very low certainty).

1 finding from 1 review

Intervention not reported

Immediate postoperative anxiety (VAS) VAS (0 to 100 mm) measured approximately 90 minutes after surgery or in recovery room 0: no anxiety 100: maximum anxiety possible · patients undergoing elective surgery
1 finding from 1 review

Intervention not reported

Postoperative anxiety (6‐item STAI) STAI 6‐item (6 to 24) measured 1 hour and 6 hours after surgery 6: no anxiety 24: maximum anxiety possible · patients undergoing elective surgery
1 finding from 1 review

Intervention not reported

Immediate postoperative anxiety (VAS) VAS (0 to 100 mm) measured after surgery, in recovery, or at discharge from recovery room 0: no anxiety 100: maximum anxiety possible · patents undergoing elective surgery
1 finding from 1 review