Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,227 questions · 2,562 findings · 156 reviews · All outcomes

No studies found 297 · 11.6%GRADE not reported 1,616 · 63.1%Very low 405 · 15.8%Low 144 · 5.6%Moderate 81 · 3.2%High 19 · 0.7%

Gingivitis (assessed by gingival index or WHO criteria) vs Individuals without gingivitis

Oral health-related quality of life · Indians

Continuous analyses (GOHAI, OHIP-14) of gingivitis and OHRQoL were inconsistent and mostly non-significant; ungraded.

2 findings from 1 review

Dental caries vs Absence/lower severity of dental caries

Oral health-related quality of life · Adolescents (10-19 years)

Dental caries is associated with worse OHRQoL in adolescents, with greater severity linked to greater impact (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The impact of dental caries on OHRQoL was addressed in five systematic reviews [9, 26, 34, 36, 37]. Three articles report that the greater the severity of the carious lesion, the worse the impact on OHRQoL in…
    5 studies
    GRADE not reported

Female sex vs Male sex

Oral health-related quality of life · Adolescents (10-19 years)

The abstract reports female sex is associated with worse OHRQoL, but the conclusion states the impact of gender was not clarified (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Dental caries vs Caries-free controls

Oral health-related quality of life · Indian children aged 3-5 years

In children aged 3-5 years, early childhood caries was significantly associated with poorer OHRQoL (narrative; 3 studies); ungraded.

1 finding from 1 review

Higher family income / socioeconomic status vs Lower income / worse socioeconomic status

Oral health-related quality of life · Adolescents (10-19 years)

Higher family income / better socioeconomic status is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Worse oral health status, older age, female sex and worse socioeconomic status were significantly…
    Studies not reported
    GRADE not reported

Completed orthodontic treatment vs Untreated / never received orthodontic treatment

Oral health-related quality of life · Adolescents (10-19 years)

Completing orthodontic treatment is associated with improved OHRQoL in adolescents (narrative synthesis; included reviews report low-to-moderate certainty; no pooled estimate or GRADE rating by the umbrella review).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents who had never received orthodontic treatment had a greater impact on quality of life compared to patients who had already completed treatment [34, 40, 44-46]. Orthodontic treatment during childhood or…
    Studies not reported
    GRADE not reported

Prosthetic need vs Individuals without prosthetic need

Oral health-related quality of life · Indian elderly and general-population adults

Prosthetic need was significantly associated with poorer OHRQoL in both included studies (moderate certainty).

3 findings from 1 review

Missing teeth / tooth loss vs No tooth loss

Oral health-related quality of life · Adolescents (10-19 years)

Tooth loss/edentulism is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review

Bruxism vs No bruxism

Oral health-related quality of life · Adolescents (10-19 years)

Bruxism was not shown to impact OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Dental erosion vs No dental erosion

Oral health-related quality of life · Adolescents (10-19 years)

The umbrella review reported that dental erosion has not been shown to affect oral health-related quality of life.

2 findings from 1 review

Dental fluorosis (assessed by TFI or WHO criteria) vs Individuals without dental fluorosis

Oral health-related quality of life · Indian children and young adults

Two studies found dental fluorosis significantly associated with poorer OHRQoL; narrative, ungraded.

1 finding from 1 review

Favorable socioeconomic and family environment vs Less favorable socioeconomic and family environment

Oral health-related quality of life · Adolescents (10-19 years)

The umbrella review reported better oral health-related quality of life with favorable housing, parental education, income, family environment, and access to dental care.

1 finding from 1 review

Poor / irregular toothbrushing vs Toothbrushing alone

Oral health-related quality of life · Adolescents (10-19 years)

Irregular/poor toothbrushing is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    The systematic review reports factors that physical disability, visual impairment, mental disorders, poor diet and irregular brushing negatively impact OHRQoL [36].
    Studies not reported
    GRADE not reported

Temporomandibular disorder vs No temporomandibular disorder

Oral health-related quality of life · Adolescents (10-19 years)

Temporomandibular disorder is associated with worse OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

2 findings from 1 review

Higher parental / maternal education vs Lower parental education (reference)

Oral health-related quality of life · Adolescents (10-19 years)

Higher parental education is associated with better OHRQoL in adolescents (narrative synthesis; no pooled estimate or GRADE rating).

1 finding from 1 review
  • Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomes
    Community/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
    Adolescents from families with higher incomes and higher levels of maternal education have better OHRQoL scores [34]. Children from families with high income, parental education and family economy had better OHRQoL [42].
    Studies not reported
    GRADE not reported