Findings

What do systematic reviews say?

1,230 questions · 1,303 findings · 326 reviews · Headline outcomes only

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No studies found 73 · 5.6%GRADE not reported 21 · 1.6%Very low 497 · 38.1%Low 403 · 30.9%Moderate 245 · 18.8%High 64 · 4.9%

Summary of findings: insulin degludec vs insulin glargine

Health related quality of life the Uniscale and the Symptom Distress Scale (SDS); Better indicated by lower values

1 finding from 1 review

(Ultra‐)long‐acting insulin analogues for people with type 1 diabetes mellitus 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1042 participants
Very low

Anti‐IL‐4Rα mAb (dupilumab) vs placebo (on top of topical steroids)

Generic quality of life measures · patients with severe chronic rhinosinusitis with nasal polyps

1 finding from 1 review

Biologics for chronic rhinosinusitis 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 766 participants
Moderate

Active stimulation + other intervention vs other intervention alone

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · adults with chronic pain

3 findings from 1 review

Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 303 participants
Very low
Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 635 participants
Low
Implanted spinal neuromodulation interventions for chronic pain in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Virtual reality training vs wet laboratory or no supplementary training

Simulator task ratings (range 0–100; higher score indicates better performance) · ophthalmology trainees for cataract surgery

1 finding from 1 review

Virtual reality training for cataract surgery operating performance in ophthalmology trainees 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Virtual reality training vs wet laboratory or no supplementary training

Supervising physician ratingsin simulated settings (range 0–100; higher score indicates better performance) · ophthalmology trainees for cataract surgery

1 finding from 1 review

Virtual reality training for cataract surgery operating performance in ophthalmology trainees 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Breathing exercises vs inactive control

Change in AQLQ · adults with asthma

1 finding from 1 review

Breathing exercises for adults with asthma 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 974 participants
Moderate

Radiotherapy combined with anti‐VEGF vs anti‐VEGF alone

Contrast sensitivity (log contrast threshold) Measured using a Pelli‐Robson chart. Higher scores represent better contrast sensitivity. · people with neovascular AMD

The review found no eligible studies for this question.

1 finding from 1 review

Radiotherapy for neovascular age‐related macular degeneration 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Radiotherapy vs control

Contrast sensitivity (log contrast threshold) Measured using a Pelli‐Robson chart. Higher scores represent better contrast sensitivity. · people with neovascular AMD

1 finding from 1 review

Radiotherapy for neovascular age‐related macular degeneration 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Any pessary vs pelvic floor muscle training (PFMT)

Improvement or cure of associated sexual symptoms · pelvic organ prolapse in women

1 finding from 1 review

Pessaries (mechanical devices) for managing pelvic organ prolapse in women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Low

Any pessary vs control, waiting list or no active treatment

Patients perceived improvement in symptoms of prolapse assessed using validated symptom questionnaire at 1 year ‐ not reported · pelvic organ prolapse in women

1 finding from 1 review

Pessaries (mechanical devices) for managing pelvic organ prolapse in women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low

Any pessary vs pelvic floor muscle training (PFMT)

Patients perceived improvement in symptoms of prolapse assessed using validated symptom questionnaire at 1 year ‐ not reported · pelvic organ prolapse in women

1 finding from 1 review

Pessaries (mechanical devices) for managing pelvic organ prolapse in women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Low

Any pessary vs pelvic floor muscle training (PFMT)

Prolapse‐specific quality of life · pelvic organ prolapse in women

1 finding from 1 review

Pessaries (mechanical devices) for managing pelvic organ prolapse in women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 116 participants
Low

Cognitive behavioural therapy as vs standard‐of‐care therapy

Quality of life As assessed by QOLIE31 (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

1 finding from 1 review

Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
Very low

Specialised cognitive behavioural therapy‐based physiotherapy vs WAIT LIST

Level of functioning · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

1 finding from 1 review

Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Low

Hypnosis plus treatment as usual vs treatment

Reduction in physical signs (Severity of impairment) Measured by the VRMC scale (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

1 finding from 1 review

Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low

Hypnosis vs WAIT LIST

Reduction in physical signs (Severity of impairment) Measured by the VRMC scale (higher is better) · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

1 finding from 1 review

Psychosocial interventions for conversion and dissociative disorders in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Low

CBT vs AC

Reduction in pain intensity · chronic pain (excluding headache) in adults

1 finding from 1 review

Psychological therapies for the management of chronic pain (excluding headache) in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
23 studies · 3235 participants
Moderate

CBT vs TAU

Functional disability at 3 months ‐ not measured · chronic pain (excluding headache) in adults

1 finding from 1 review

Psychological therapies for the management of chronic pain (excluding headache) in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 2524 participants
Low

CBT vs TAU

Distress at · chronic pain (excluding headache) in adults

1 finding from 1 review

Psychological therapies for the management of chronic pain (excluding headache) in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
27 studies · 2559 participants
Moderate

CBT vs TAU

AEs · chronic pain (excluding headache) in adults

1 finding from 1 review · compare the 2 reviews

Psychological therapies for the management of chronic pain (excluding headache) in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1314 participants
Very low