Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

TLS with conventional morphological assessment of still TLS images vs conventional incubation and assessment

Clinical pregnancy · couples undergoing assisted reproductive technology

TLS with conventional morphological assessment of still TLS images showed no clear difference in clinical pregnancy compared with conventional incubation and assessment (low certainty).

1 finding from 1 review

TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images

Live birth or ongoing pregnancy · couples undergoing assisted reproductive technology

It is very uncertain whether TLS utilising embryo selection software changes live birth or ongoing pregnancy compared with TLS with conventional morphological assessment of still TLS images (very low certainty).

1 finding from 1 review

TLS utilising embryo selection software vs TLS with conventional morphological assessment of still TLS images

Clinical pregnancy · couples undergoing assisted reproductive technology

It is very uncertain whether TLS utilising embryo selection software changes clinical pregnancy compared with TLS with conventional morphological assessment of still TLS images (very low certainty).

1 finding from 1 review

TLS utilising embryo selection software vs conventional incubation and assessment

Live birth or ongoing pregnancy · couples undergoing ART

It is very uncertain whether TLS utilising embryo selection software changes live birth or ongoing pregnancy compared with conventional incubation and assessment (very low certainty).

1 finding from 1 review

Long‐term GnRH agonist therapy vs no additional therapy

Clinical pregnancy rate · patients with endometriosis prior to standard IVF/ICSI

It is very uncertain whether long‐term GnRH agonist therapy changes clinical pregnancy rate compared with no additional therapy (very low certainty).

1 finding from 1 review

Long‐term GnRH agonist therapy vs no additional therapy

Multiple pregnancy rate · patients with endometriosis prior to standard IVF/ICSI

It is very uncertain whether long‐term GnRH agonist therapy changes multiple pregnancy rate compared with no additional therapy (very low certainty).

1 finding from 1 review

Timing of insemination for intrauterine insemination with donor sperm: luteinising hormone (LH) + 1 day vs LH + 2 days

Clinical pregnancy rate · women starting donor sperm treatment

It is very uncertain whether timing of insemination for intrauterine insemination with donor… changes clinical pregnancy rate compared with LH + 2 days (very low certainty).

1 finding from 1 review

Timing of intrauterine insemination with donor sperm: urinary luteinising hormone test vs temperature curve and cervical mucus score

Clinical pregnancy rate · women starting donor sperm treatment

It is very uncertain whether timing of intrauterine insemination with donor sperm: urinary… changes clinical pregnancy rate compared with temperature curve and cervical mucus score (very low certainty).

1 finding from 1 review

Intrauterine insemination vs intracervical insemination

Clinical pregnancy rate · women starting donor sperm treatment

It is very uncertain whether intrauterine insemination changes clinical pregnancy rate compared with intracervical insemination (very low certainty).

2 findings from 1 review

Conscious sedation and analgesia (CSA) + paracervical block (PCB) vs electro‐acupuncture + PCB

Pregnancy · women undergoing oocyte retrieval for assisted reproduction

Conscious sedation and analgesia (CSA) + paracervical block (PCB) showed no clear difference in pregnancy compared with electro‐acupuncture + PCB (low certainty).

1 finding from 1 review

Conscious sedation and analgesia (CSA) + paracervical block (PCB) vs general anaesthesia

Pregnancy · women undergoing oocyte retrieval for assisted reproduction

It is very uncertain whether conscious sedation and analgesia (CSA) + paracervical block (PCB) changes pregnancy compared with general anaesthesia (very low certainty).

1 finding from 1 review