Cochrane · systematic review · CD012856

Screening hysteroscopy in subfertile women and women undergoing assisted reproduction

Kamath, MS, Bosteels, J, D'Hooghe, TM, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 62.5%Low 3 · 37.5%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Screening hysteroscopy versus no hysteroscopy in women wishing to conceive spontaneously

Population: women with unexplained subfertility wishing to conceive spontaneously
4 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Screening hysteroscopy vs no hysteroscopy
RR 4.3 [2.29, 8.07]1 study · 200 participantsVery low
Downgraded: risk of bias, indirectness
Adverse events
Screening hysteroscopy vs no hysteroscopy
no estimate extracted1 study · 1 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Clinical pregnancy
Screening hysteroscopy vs no hysteroscopy
RR 3.8 [2.31, 6.24]1 study · 200 participantsVery low
Downgraded: risk of bias, indirectness
Miscarriage
Screening hysteroscopy vs no hysteroscopy
RR 2.8 [1.05, 7.48]1 study · 200 participantsVery low
Downgraded: risk of bias, imprecision, indirectness

Screening hysteroscopy versus no hysteroscopy in women before IVF

Population: women before IVF treatment
4 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth
Screening hysteroscopy vs no hysteroscopy
RR 1.26 [1.11, 1.43]6 studies · 2745 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Adverse events
Screening hysteroscopy vs no hysteroscopy
Peto OR 7.47 [0.15, 376.42]4 studies · 1872 participantsVery low
Downgraded: risk of bias, imprecision
Clinical pregnancy
Screening hysteroscopy vs no hysteroscopy
RR 1.32 [1.2, 1.45]10 studies · 3750 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Miscarriage
Screening hysteroscopy vs no hysteroscopy
RR 1.01 [0.67, 1.5]3 studies · 1669 participantsLow
Downgraded: risk of bias, imprecision