Participant‐reported pain relief of 30% or greater · adults with painful diabetic neuropathy
It is very uncertain whether topical clonidine (TC) changes participant‐reported pain relief of 30% or greater during longest compared with placebo (very low certainty).
1 finding from 1 review
Patient Global Impression of Change much or very much improved · adults with painful diabetic neuropathy
Topical clonidine (TC) showed no clear difference in much or very much improved on PGIC during longest compared with placebo (low certainty).
1 finding from 1 review
PGIC very much improved · adults with painful diabetic neuropathy
Topical clonidine (TC) showed no clear difference in very much improved on PGIC during longest compared with placebo (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults with painful diabetic neuropathy
Topical clonidine (TC) showed no clear difference in withdrawals due to adverse events during longest compared with placebo (low certainty).
1 finding from 1 review
Number of participants reporting an adverse event · adults with painful diabetic neuropathy
Topical clonidine (TC) showed no clear difference in participants experiencing at least 1adverse event during longest compared with placebo (low certainty).
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · adults with painful diabetic neuropathy
Topical clonidine (TC) showed no clear difference in participant‐reported pain relief of 50% or greater during longest compared with active comparator (low certainty).
1 finding from 1 review
Participant‐reported pain relief of 30% or greater · adults with painful diabetic neuropathy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Longer term (> 1 year after disease onset) coronary morbidity (non‐aneurysmal) · children diagnosed with Kawasaki disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effect: mean days of prolonged vaginal bleeding within 6 weeks postpartum · postpartum people who desire a contraceptive implant for contraception
Immediate may leads to higher adverse effect: mean days of prolonged vaginal bleeding within 6… compared with delayed postpartum insertion of contraceptive implants (low certainty).
1 finding from 1 review
Adverse effects other than prolonged vaginal bleeding · postpartum people who desire a contraceptive implant for contraception
Immediate may leads to higher adverse effects other than prolonged vaginal bleeding compared with delayed postpartum insertion of contraceptive implants (low certainty).
1 finding from 1 review
Recurrent VTE · people requiring treatment for chronic DVT
Chronic DVT ‐ antiplatelet agents plus BMP may leads to lower recurrent VTE ‐ early, intermediate and long term compared with BMP plus placebo (low certainty).
1 finding from 1 review
Mortality ‐ intermediate and long term · people requiring treatment for chronic DVT
Chronic DVT ‐ antiplatelet agents plus BMP showed no clear difference in mortality ‐ intermediate and long term compared with BMP plus placebo (moderate certainty).
1 finding from 1 review
Participants' health status and well‐being · Indigenous children aged < 5 years
1 finding from 1 review
Psychological health and emotional behaviour of children Timing: the longest time point available for each study Direction of effect: higher beneficial · Indigenous children aged < 5 years
1 finding from 1 review
Physical health and developmental health outcomes of children Timing: the longest time point available for each study Direction of effect: higher beneficial · Indigenous children aged < 5 years
1 finding from 1 review
Family health‐enhancing lifestyle or behavioural outcomes Timing: the longest time point available for each study Direction of effect: higher beneficial · Indigenous children aged < 5 years
1 finding from 1 review
Psychological health of parent/carer Timing: the longest time point available for each study Direction of effect: higher beneficial · Indigenous children aged < 5 years
1 finding from 1 review
Fistula closure in long‐term · Induction of Remission in Medically Refractory Crohn's Disease
Summary of findings table ‐ Stem Cell may leads to higher fistula closure in long‐term compared with placebo or Control (low certainty).
1 finding from 1 review
Intervention not reported
Long cephalomedullary nail (2 studies; 400 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
It is very uncertain whether the intervention changes long cephalomedullary nail (2 studies; 400 participants)a (very low certainty).
1 finding from 1 review
Intervention not reported
Long cephalomedullary nail (2 studies; 400 participants)a · older adults (> 60 years of age) with extracapsular hip fractures
It is very uncertain whether the intervention changes long cephalomedullary nail (2 studies; 400 participants)a (very low certainty).
1 finding from 1 review