Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

489 questions · 504 findings · 104 reviews

No studies found 32 · 6.3%GRADE not reported 63 · 12.5%Very low 152 · 30.2%Low 133 · 26.4%Moderate 103 · 20.4%High 21 · 4.2%

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Antibiotic use: delayed (all strategies) versus no antibiotics · respiratory infections

Summary of findings table ‐ Delayed antibiotics probably leads to higher antibiotic use: delayed (all strategies) versus no antibiotics compared with no antibiotics (moderate certainty).

1 finding from 1 review

ISBCS vs DSBCS

Proportion of participants with endophthalmitis · people with bilateral age‐related cataracts (NRSs)
2 findings from 1 review

ISBCS vs DSBCS

Complications · people with bilateral age‐related cataracts (NRSs)

It is very uncertain whether ISBCS changes complications compared with DSBCS (very low certainty).

2 findings from 1 review

ISBCS vs DSBCS

Total costs per QALY · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

BCDVA · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Patient‐reported outcome measures (PROMs) · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Refraction NOT within 1.0 dioptres of target · people with bilateral age‐related cataracts (NRSs)

ISBCS showed no clear difference in refraction NOT within 1.0 dioptres of target compared with DSBCS (moderate certainty).

2 findings from 1 review

Very early cerebral revascularization vs delayed treatment

Perioperative death and strokes · people with recently symptomatic carotid artery stenosis

It is very uncertain whether very early cerebral revascularization changes stroke and Death < 30 days compared with delayed treatment (very low certainty).

2 findings from 1 review

Intervention not reported

Expulsion by 6 months · postpartum women with desire for contraceptive

The intervention showed no clear difference in expulsion by 6 months (moderate certainty).

1 finding from 1 review