Cochrane · systematic review · CD009836

Immediate referral to colposcopy versus cytological surveillance for minor cervical cytological abnormalities in the absence of HPV test

Kyrgiou, M, Kalliala, I, Mitra, A, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 4 · 57.1%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: occurrence of CIN and default rates

Population: women with ASCUS or LSIL
7 questions
OutcomeEffectEvidenceStatus / GRADE
Occurrence of CIN2+ in histology at 18 months
RR 1.5 [1.12, 2.01]2 studies · 4028 participantsModerate
Downgraded: inconsistency
Occurrence of CIN2+ in histology at 24 months
RR 1.14 [0.66, 1.97]3 studies · 4331 participantsLow
Downgraded: inconsistency
Occurrence of CIN3+ in histology at 18 months
RR 1.24 [0.77, 1.98]2 studies · 4028 participantsModerate
Downgraded: inconsistency
Occurrence of CIN3+ in histology at 24 months
RR 1.02 [0.53, 1.97]3 studies · 4331 participantsLow
Downgraded: inconsistency
Occurrence of any CIN in histology at 24 months
RR 2.02 [1.33, 3.08]2 studies · 656 participantsLow
Downgraded: inconsistency
Default rates at 6 months
RR 3.85 [1.27, 11.63]3 studies · 5117 participantsModerate
Downgraded: inconsistency
Default rates at 12 months
RR 6.63 studies · 5115 participantsModerate
Downgraded: inconsistency