Cochrane · systematic review · CD013270

Immediate sequential bilateral surgery versus delayed sequential bilateral surgery for cataracts

Dickman, MM, Spekreijse, LS, Winkens, B, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
10
No studies
4
Included studies
NR
No studies 4 · 28.6%Ungraded 0 · 0%Very low 4 · 28.6%Low 4 · 28.6%Moderate 2 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

ISBCS compared to DSBCS in people with bilateral age‐related cataracts (RCTs)

Population: people with bilateral age‐related cataracts (RCTs)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Endophthalmitis
ISBCS vs DSBCS
no estimate extracted2 studies · 1309 participantsLow
Downgraded: imprecision
Refraction NOT within 1.0 dioptres of target
ISBCS vs DSBCS
RR 0.84 [0.57, 1.26]1 study · 982 participantsModerate
Downgraded: imprecision
Complications
ISBCS vs DSBCS
RR 1.33 [0.52, 3.4]2 studies · 1305 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Total costs per participant
ISBCS vs DSBCS
no estimate extracted1 study · 1 participantsLow
Downgraded: risk of bias, indirectness
Total costs per QALY
ISBCS vs DSBCS
no estimate extractedNRNo studies
BCDVA
ISBCS vs DSBCS
no estimate extracted2 studies · 2 participantsVery low
Downgraded: imprecision, inconsistency, indirectness
PROMs
ISBCS vs DSBCS
no estimate extracted2 studies · 1297 participantsModerate
Downgraded: risk of bias

ISBCS compared to DSBCS in people with bilateral age‐related cataracts (NRSs)

Population: people with bilateral age‐related cataracts (NRSs)
7 questions
OutcomeEffectEvidenceStatus / GRADE
Endophthalmitis
ISBCS vs DSBCS
RR 1.97 [0.32, 12.16]7 studies · 570322 participantsLow
Downgraded: risk of bias, imprecision
Refraction NOT within 1.0 dioptres of target
ISBCS vs DSBCS
RR 1.02 [0.6, 1.75]3 studies · 946 participantsLow
Downgraded: risk of bias, imprecision
Complications
ISBCS vs DSBCS
RR 1.04 [0.47, 2.29]5 studies · 25739 participantsVery low
Downgraded: risk of bias, inconsistency
Total costs per participant
ISBCS vs DSBCS
no estimate extracted4 studies · 4 participantsVery low
Downgraded: risk of bias
Total costs per QALY
ISBCS vs DSBCS
no estimate extractedNRNo studies
BCDVA
ISBCS vs DSBCS
no estimate extractedNRNo studies
PROM
ISBCS vs DSBCS
no estimate extractedNRNo studies