Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,163 questions · 1,209 findings · 133 reviews · Headline outcomes only

No studies found 176 · 14.6%GRADE not reported 47 · 3.9%Very low 241 · 19.9%Low 323 · 26.7%Moderate 315 · 26.1%High 107 · 8.9%

Intervention not reported

Number of participants requiring oral corticosteroids over the study period · Adults from minority groups with doctor diagnosed asthma

It is very uncertain whether the intervention changes number of participants requiring oral corticosteroids over the study… (very low certainty).

1 finding from 1 review

Intervention not reported

Antibiotic prescriptions (number of courses/person/year) **Corticosteroids not meta‐analysed · adults (> 18 years of age) with either COPD or recurrent acute exacerbations of chronic bronchitis

The intervention may leads to higher antibiotic prescriptions (number of courses/person/year)… (low certainty).

1 finding from 1 review

Intervention not reported

Exacerbations requiring oral corticosteroids 7.3‐month · people with asthma

The intervention showed no clear difference in exacerbations requiring oral corticosteroids 7.3‐month (low certainty).

1 finding from 1 review

Intervention not reported

Exacerbations requiring oral corticosteroids3 months · adults or children with asthma

The intervention showed no clear difference in exacerbations requiring oral corticosteroids3 months (low certainty).

1 finding from 1 review

Intermittent ICS vs placebo

Exacerbations requiring oral corticosteroids ‐ School‐age children · School‐aged children and adults

Intermittent ICS showed no clear difference in exacerbations requiring oral corticosteroids ‐ School‐age children compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Asthma exacerbation as defined by hospital admission or treatment with a course of oral corticosteroids · participants with asthma

The review found no eligible studies for this question.

1 finding from 1 review