Findings

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Evidence found and GRADE certainty

900 questions · 932 findings · 149 reviews

No studies found 215 · 23.1%GRADE not reported 65 · 7%Very low 234 · 25.1%Low 256 · 27.5%Moderate 134 · 14.4%High 28 · 3%

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous) - individual taste sensations · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… showed no clear difference in taste acuity improvement - objective outcome (continuous) -… compared with placebo; GRADE not reported.

1 finding from 1 review
  • Interventions for managing taste disturbances 2017 · Cochrane All outcomes
    Chronic renal failure
    Results (Mahajan 1980, chronic renal failure; Analysis 1.3): mean difference by taste sensation - salt MD 285 (95% CI 238.75 to 331.25); sweet MD 190 (142.36 to 237.64); sour MD 10 (-16.43 to 36.43); bitter MD 2.40…
    1 study · 22 participants
    GRADE not reported

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous) - taste detection (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).

1 finding from 1 review

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous) - taste recognition (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).

1 finding from 1 review

Admission cardiotocography vs intermittent auscultation

Incidence of continuous electronic fetal monitoring during labour · Low risk pregnant women. All of the women were in labour.

Admission cardiotocography may leads to higher incidence of continuous electronic fetal monitoring during labour compared with intermittent auscultation (low‐risk women) (low certainty).

1 finding from 1 review

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous data) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous data) compared with placebo (very low certainty).

1 finding from 1 review

Pilocarpine vs no treatment/placebo

Dry mouth (xerostomia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region

It is very uncertain whether pilocarpine changes xerostomia (continuous, combined SMD) compared with no treatment/placebo (very low certainty).

1 finding from 1 review

Preoperative ibuprofen vs placebo

Postoperative pain (continuous measure: self report using visual analogue scale) · Children and adolescents having orthodontic separator placement (without local anaesthetic)

Preoperative ibuprofen may leads to lower postoperative pain (continuous measure: self report using visual… compared with placebo (low certainty).

1 finding from 1 review

Antipsychotics vs placebo

Continuous abstinence (number of participants who maintained negative drug screens for 2 ‐ 3 weeks) Number of participants that maintained negative cocaine screens for at least 2 ‐ 3 weeks · patients with the treatment of cocaine dependence

Any antipsychotic showed no clear difference in continuous abstinence (number of participants who maintained… compared with placebo (low certainty).

1 finding from 1 review