Question · asked by 1 review

Preoperative ibuprofen vs placebo: Postoperative pain (continuous measure: self report using visual analogue scale)

Population
Children and adolescents having orthodontic separator placement (without local anaesthetic)
Intervention
Preoperative ibuprofen
Comparison
placebo
Outcome
Postoperative pain (continuous measure: self report using visual analogue scale)

Preoperative ibuprofen may leads to lower postoperative pain (continuous measure: self report using visual… compared with placebo (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Preoperative ibuprofen vs Placebo
Postoperative pain (continuous measure: self report using visual analogue scale) · Children and adolescents having orthodontic separator placement (without local anaesthetic) · 2 hours
Preoperative ibuprofen may leads to lower postoperative pain (continuous measure: self report using visual… compared with placebo (low certainty).
Preoperative analgesics for additional pain relief in children and adolescents having dental treatment (2016) · Cochrane All outcomes
MD -13.44 [-23.01, -3.88]2 studies · 85 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Preoperative analgesics for additional pain relief in children and adolescents having dental treatment
2016 · Cochrane All outcomes
2016-01Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.