Question · asked by 1 review

Zinc vs placebo: Taste acuity improvement - objective outcome (continuous) - taste detection (cross-over trial)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate, zinc acetate, or polaprezinc) vs Placebo
Taste acuity improvement - objective outcome (continuous) - taste detection (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal… · 6 months, Children with chronic renal failure
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous) - taste… compared with placebo (very low certainty).
Interventions for managing taste disturbances (2017) · Cochrane All outcomes
MD 2.50 [0.93, 4.07]1 study · 14 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing taste disturbances
2017 · Cochrane All outcomes
2017-07list not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.