Same question across reviews · CL0286
intervention :: Unclassified intervention -> Diagnostic accuracy
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
16
Questions
82
current versions
GRADE rated
15
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Periodontal treatment: scaling and root planing (SRP) plus advice vs Community care: advice only Serum high-sensitivity C-reactive protein (hs-CRP) · People with cardiovascular disease and chronic periodontitis · 12 months Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis (2022) · Cochrane | Serum hs-CRP tested at one year; as loss to follow-up was almost 90%, data not considered useful for analysis (no usable estimate). | 1 study · 37 participants | Ungraded |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's submental region (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD 0.52 [-0.11, 1.16] | 1 study · 47 participants | Ungraded |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's occiput (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD 0.77 [-0.46, 2.00] | 1 study · 47 participants | Very low |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at 2 metres from mouth (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD -11.70 [-15.82, -7.58] | 1 study · 10 participants | Very low |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at 2 metres from mouth (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD -2.80 [-4.65, -0.95] | 1 study · 20 participants | Ungraded |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at 1 metre from mouth (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD -10.10 [-19.72, -0.48] | 1 study · 20 participants | Ungraded |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's left ear (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD 0.96 [-0.08, 2.00] | 1 study · 47 participants | Ungraded |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at operator's forehead (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD 0.98 [-0.73, 2.70] | 1 study · 47 participants | Very low |
Rubber dam + HVE vs Cotton roll + HVE Reduction in level of contamination in aerosols (CFU) during restorative procedures at dental unit light · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD -12.70 [-12.85, -12.55] | 1 study · 21 participants | Very low |
Rubber dam vs No rubber dam Reduction in level of contamination in aerosols (CFU) during restorative procedures at 1 metre from mouth (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD -16.20 [-19.36, -13.04] | 1 study · 10 participants | Very low |
Rubber dam + HVE vs Cotton roll + HVE Reduction in level of contamination in aerosols (CFU) during restorative procedures at participant's chest · People undergoing aerosol-generating procedures (AGPs) in a dental setting Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious… (2020) · Cochrane | MD -251.00 [-267.95, -234.05] | 1 study · 21 participants | Very low |
Acupressure at P6 point with thumb vs Sham (dummy) acupressure Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 0.85 [0.50, 1.46] | 1 study · 30 participants | Very low |
Acupuncture at P6 point vs Sham acupuncture Successful completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 1.78 [1.05, 3.01] | 2 studies · 59 participants | Very low |
Acupressure at P6 point with device plus sedation vs Sham (dummy) acupressure with sedation Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 1.16 [0.90, 1.48] | 1 study · 27 participants | Very low |
Acupressure at P6 point with device vs Sham (dummy) acupressure Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 2.63 [1.33, 5.18] | 1 study · 34 participants | Very low |
Acupuncture at P6 point with sedation vs Sham (dummy) acupuncture with sedation Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 1.08 [0.91, 1.28] | 1 study · 34 participants | Very low |
Acupressure at P6 point with sea band plus sedation vs Sham (dummy) acupressure with sedation Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 0.88 [0.67, 1.17] | 1 study · 21 participants | Very low |
Acupressure at P6 point with sea band vs Sham (dummy) acupressure Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 1.80 [0.63, 5.16] | 1 study · 19 participants | Very low |
Acupressure at P6 point with thumb plus sedation vs Sham (dummy) acupressure with sedation Completion of dental procedure · People (older than four years) classified as having gagging that interfered with dental treatment; included trials… Management of gag reflex for patients undergoing dental treatment (2019) · Cochrane | RR 0.96 [0.84, 1.10] | 1 study · 39 participants | Very low |
4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine Participants' experience of the procedures · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario… Injectable local anaesthetic agents for dental anaesthesia (2018) · Cochrane | No data from the included studies were available. | 0 studies | No studies |
Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations · 12 months Meta-analysis of the clinical behavior of posterior direct resin restorations: Low polymerization shrinkage… (2018) | OR 1.65 [0.71, 3.81] | 10 studies · 970 participants | Ungraded |
GTR rm + CAF vs GTR nrm + CAF Patients' preference for a specific procedure · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm) · Short term (6 to 12 months) Root coverage procedures for treating localised and multiple recession‐type defects (2018) · Cochrane | Roccuzzo 1996: all patients preferred the GTR treatment because it was a single-step procedure | 1 study | Ungraded |
Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Another active intervention, placebo, or no treatment Patient-reported outcomes related to pain or discomfort during the procedure · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior,… Interventions for treating post‐extraction bleeding (2018) · Cochrane | No data are available as no RCTs have been conducted on interventions to treat post-extraction bleeding | 0 studies | No studies |
Low polymerization shrinkage resin composite (silorane, ormocer, bulk-fill or other modified-monomer composite) vs Conventional methacrylate-based resin composite Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations · 24 months Meta-analysis of the clinical behavior of posterior direct resin restorations: Low polymerization shrinkage… (2018) | Six articles (seven experimental groups) evaluated postoperative sensitivity after 24 months; four showed no sensitivity in either group and three favored the control group, but the overall meta-analytic effect was not… | 6 studies | Ungraded |
GTR rm + CAF vs SCTG + CAF Patients' preference for a specific procedure · Adult patients with single (localised) recession-type defects (Miller Class I/II, at least 3 mm) · Short term (6 to 12 months) Root coverage procedures for treating localised and multiple recession‐type defects (2018) · Cochrane | Wang 2001: participants reported greater overall satisfaction with GTR rm than SCTG (reduced treatment time, no need for a second surgical site) | 1 study | Ungraded |
Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate, zinc acetate, or polaprezinc) vs Placebo Taste acuity improvement - objective outcome (continuous) - taste detection (cross-over trial) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal… · 6 months, Children with chronic renal failure Interventions for managing taste disturbances (2017) · Cochrane | MD 2.50 [0.93, 4.07] | 1 study · 14 participants | Very low |
Bone substitute (anorganic bovine bone / Bio-Oss) vs A different bone substitute Augmentation procedure failure · Patients undergoing two-stage maxillary sinus augmentation · 1 year after loading Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane | Augmentation procedure failure 0/11 versus 0/11; none. | 1 study · 11 participants | Ungraded |
Maxillary sinus lift (augmentation) with long implants vs Short implants (5 to 8.5 mm) without sinus augmentation Augmentation procedure failure · Patients with missing teeth and an atrophic posterior maxilla, with residual bone height between 4 and 9 mm below the… · 1 year after loading Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane | One bilateral augmentation failure occurred in one trial only (Felice 2011). | 1 study | Ungraded |
Rotary instruments to open the lateral sinus window vs Piezosurgery to open the lateral sinus window Augmentation procedure failure · Patients undergoing lateral-window maxillary sinus lift · 1 year after loading Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane | Rickert 2013 (N = 36): no augmentation procedure failures. | 1 study · 36 participants | Ungraded |
Hand mallet (osteotomes) vs Electric mallet Augmentation procedure failure · Patients undergoing one-stage crestal maxillary sinus lift without bone grafts (baseline residual bone height about… · 19 months to 3 years after loading Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane | Augmentation failures 0/40 versus 0/40; none. | 1 study · 80 participants | Ungraded |
Sinus lift with bone graft (granular Bio-Oss) vs Sinus lift without bone graft (Inion resorbable rigid barrier maintaining space / no bone) Augmentation procedure failure · Patients with an atrophic maxillary sinus requiring augmentation (1 to 5 mm residual bone height) · 1 year after loading Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane | OR 0.48 [0.04, 5.67] | 1 study · 44 participants | Ungraded |
One-stage crestal-approach sinus lift with autogenous bone and 8 mm implants vs Lateral-window sinus lift with 50% autogenous bone/50% Bio-Oss and implants at least 10 mm long Augmentation (graft) procedure failure · Patients with 3 to 6 mm of residual bone height at the sinus floor · 5 years after loading Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus (2014) · Cochrane | OR 0.18 [0.01, 4.01] | 1 study · 40 participants | Ungraded |
Visual screening (oral visual inspection) by trained health workers vs No screening Stage at diagnosis (early-stage detection) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 15-year follow-up Screening programmes for the early detection and prevention of oral cancer (2013) · Cochrane | RR 0.81 [0.70, 0.93] | 1 study · 523 participants | Ungraded |
Visual screening (oral visual inspection) by trained health workers vs No screening Test performance (sensitivity and specificity) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 15-year follow-up Screening programmes for the early detection and prevention of oral cancer (2013) · Cochrane | Across the four cycles (15 years), the reported sensitivity of the visual examination in detecting oral cancer was 67.4% (188/279). No information on the specificity or the positive predictive value of the programme… | 1 study | Ungraded |
Visual screening (oral visual inspection) by trained health workers vs No screening Stage at diagnosis (early-stage detection) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of… · 15-year follow-up, High-risk individuals (tobacco and/or alcohol users) Screening programmes for the early detection and prevention of oral cancer (2013) · Cochrane | RR 0.82 [0.71, 0.95] | 1 study · 486 participants | Ungraded |
Sodium hypochlorite 5.25% with EDTA 17% vs Sodium hypochlorite 1.3% with MTAD Mean change in health-related quality of life or participant-expressed satisfaction with the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Chlorhexidine, 0.2% to 2% (solution or gel) Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | RR 0.73 [0.34, 1.56] | 2 studies · 62 participants | Ungraded |
Sodium hypochlorite 5.25% with EDTA 17% vs Sodium hypochlorite 1.3% with MTAD Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5% (also 2.5%) vs Sodium hypochlorite 1% Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5.25% vs Normal saline Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | RR 0.8 [0.27, 2.5] | 1 study · 178 participants | Ungraded |
Sodium hypochlorite 1.3% with MTAD final rinse vs Sodium hypochlorite 1.3% with normal saline final rinse Proportion of participants with moderate to severe pain up to 6 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5% vs Sodium hypochlorite 5% with proteolytic enzyme Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | RR 0.9 [0.6, 1.5] | 1 study · 166 participants | Ungraded |
Sodium hypochlorite 5.25% vs Normal saline Proportion of participants or samples with positive bacterial growth culture, up to 72 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5% vs Sodium hypochlorite 5% with proteolytic enzyme Proportion of participants with moderate to severe pain 72 hours to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | None of the participants in either intervention group reported moderate to severe pain persisting after day 2. | 1 study · 166 participants | Ungraded |
Sodium hypochlorite 5.25% with hydrogen peroxide 3% vs Normal saline Mean change in health-related quality of life or participant-expressed satisfaction with the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5% (also 2.5%) vs Sodium hypochlorite 1% Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5.25% vs Sodium hypochlorite 5.25% with hydrogen peroxide 3% Proportion of participants with new or worsening signs/symptoms of inflammation requiring a revisit, up to 14 days after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite (NaOCl), 2.5% to 5.25% vs Chlorhexidine, 0.2% to 2% (solution or gel) Proportion of participants with moderate to severe pain up to 6 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |
Sodium hypochlorite 5.25% vs Normal saline Proportion of participants with moderate to severe pain up to 6 hours after the procedure · Patients aged 14 to 78 years with mature permanent teeth (fully formed roots), single or multi-rooted, with pulpal or… Irrigants for non‐surgical root canal treatment in mature permanent teeth (2012) · Cochrane | no estimate extracted | 0 studies | No studies |