Patients with severe exacerbations (requiring hospitalisation or ER visit) · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Asthma control · children and adults with predominantly mild to moderate asthma
1 finding from 1 review
FEV1 % predicted · children and adults with predominantly mild to moderate asthma
1 finding from 1 review
Proportion of participants with one or more serious adverse events due to any cause · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more serious adverse events… compared with placebo (high certainty).
1 finding from 1 review
People with fatal asthma exacerbation. · children and adults with predominantly mild to moderate asthma
1 finding from 1 review
Withdrawals (parallel group trials/first arm cross‐over trials) · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in withdrawals from trial compared with placebo (high certainty).
1 finding from 1 review
Death at hospital discharge · individuals with moderate to severe disease
1 finding from 1 review
Improvement of clinical status · individuals with moderate to severe disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Worsening of clinical status · individuals with moderate to severe disease
Summary of Findings Table ‐ Vitamin D showed no clear difference in worsening of clinical status compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Quality of life, including fatigue and neurological functioning; · individuals with moderate to severe disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events: all grades · individuals with moderate to severe disease
It is very uncertain whether summary of Findings Table ‐ Vitamin D changes adverse events (any grade) compared with placebo or standard care alone (very low certainty).
1 finding from 1 review
Serious adverse events · individuals with moderate to severe disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serum/plasma retinol (μmol/L) · general population over 2 years of age
1 finding from 1 review
All‐cause mortality · general population over 2 years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause morbidity · general population over 2 years of age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pre‐eclampsia · women during pregnancy
A dose of vitamin D 4000 IU/d or more showed no clear difference in pre‐eclampsia compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
1 finding from 1 review
Gestational diabetes · women during pregnancy
A dose of vitamin D 4000 IU/d or more showed no clear difference in gestational diabetes compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
1 finding from 1 review
Preterm birth · women during pregnancy
A dose of vitamin D 4000 IU/d or more showed no clear difference in preterm birth compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
1 finding from 1 review
Low birthweight · women during pregnancy
A dose of vitamin D 4000 IU/d or more showed no clear difference in low birthweight compared with 3999 IU/d or less alone or with any other nutrient (low certainty).
1 finding from 1 review
Body‐mass index (BMI) · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found