Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,271 questions · 1,326 findings · 329 reviews

No studies found 247 · 18.6%GRADE not reported 237 · 17.9%Very low 379 · 28.6%Low 285 · 21.5%Moderate 141 · 10.6%High 37 · 2.8%

Summary of findings: 3D (Tai Chi) exercise vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: 3D (Tai Chi) exercise leads to lower number of people who experienced one or more falls compared with control (e.g. usual activities) (high certainty).

1 finding from 1 review

Summary of findings: 3D (Tai Chi) exercise vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

The review found no eligible studies for this question.

1 finding from 1 review

Exercise vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: exercise (all types) leads to lower number of people who experienced one or more falls compared with control (e.g. usual activities) (high certainty).

1 finding from 1 review

Summary of findings: 3D (dance) exercise vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

It is very uncertain whether summary of findings: 3D (dance) exercise changes number of people who experienced one or more falls compared with control (e.g. usual activities) (very low certainty).

1 finding from 1 review

Summary of findings: 3D (dance) exercise vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings: walking programme (general physical activity) vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

It is very uncertain whether summary of findings: walking programme (general physical activity) changes number of people who experienced one or more falls compared with control (e.g. usual activities) (very low certainty).

1 finding from 1 review

Summary of findings: walking programme (general physical activity) vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

It is very uncertain whether summary of findings: walking programme (general physical activity) changes number of people who experienced one or more fall‐related fractures compared with control (e.g. usual activities) (very low certainty).

1 finding from 1 review

Summary of findings: multiple categories of exercise vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: multiple categories of exercise probably leads to lower number of people who experienced one or more falls compared with control (e.g. usual activities) (moderate certainty).

1 finding from 1 review

Exercise vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: exercise (all types) may leads to lower number of people who experienced one or more fall‐related fractures compared with control (e.g. usual activities) (low certainty).

1 finding from 1 review

Summary of findings: multiple categories of exercise vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: multiple categories of exercise showed no clear difference in number of people who experienced one or more fall‐related fractures compared with control (e.g. usual activities) (low certainty).

1 finding from 1 review

Exercise vs control (e.g. usual activities)

Number of people who experience a fall that required hospital admission · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

It is very uncertain whether summary of findings: exercise (all types) changes number of people who experienced one of more falls that resulted in… compared with control (e.g. usual activities) (very low certainty).

1 finding from 1 review

Exercise vs control (e.g. usual activities)

Number of people who experience a fall that required medical attention · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: exercise (all types) may leads to lower number of people who experienced one or more falls that required… compared with control (e.g. usual activities) (low certainty).

1 finding from 1 review

Summary of findings: balance and functional exercises vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: balance and functional exercises leads to lower number of people who experienced one of more falls compared with control (e.g. usual activities) (high certainty).

1 finding from 1 review

Macrolides vs tetracycline

Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease

Macrolide showed no clear difference in number of participants experiencing one or more exacerbations… compared with tetracycline (low certainty).

1 finding from 1 review

Macrolide+tetracycline vs macrolides

Number of people experiencing one or more exacerbations, Drug resistance/microbial sensitivity (as reported by trialists), including emergence of atypical bacteria, Number of participants colonised with Pseudomonas aeruginosa · patients with chronic obstructive pulmonary disease

The review found no eligible studies for this question.

1 finding from 1 review