What do systematic reviews say?

Intervention not reported

• Professional interventions for general practitioners on the management of musculoskeletal conditions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Primary care physician alerting system vs primary care physician alerting system and a patient‐directed intervention (education and reminder to see their primary care physician)

Primary care physician alerting system showed no clear difference in medication2 compared with primary care physician alerting system and a patient‐directed… (moderate certainty).

• Professional interventions for general practitioners on the management of musculoskeletal conditions 2016 · Cochrane Headline outcomes only
  RR 0.93 [0.79, 1.1]
  2 studies · 2995 participants
  Moderate

Intervention not reported

• Professional interventions for general practitioners on the management of musculoskeletal conditions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 3047 participants
  Moderate

Intervention not reported

• Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 6640 participants
  Low

Intervention not reported

• Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 1566 participants
  Low

Intervention not reported

• Automated telephone communication systems for preventive healthcare and management of long‐term conditions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 119 participants
  Low

Intervention not reported

• Automated telephone communication systems for preventive healthcare and management of long‐term conditions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 370 participants
  GRADE not reported

Intervention not reported

• Automated telephone communication systems for preventive healthcare and management of long‐term conditions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 483 participants
  Low

Intervention not reported

• Automated telephone communication systems for preventive healthcare and management of long‐term conditions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1127 participants
  Moderate

Intervention not reported

The intervention may leads to higher reduced asthma medication usage (low certainty).

• Yoga for asthma 2016 · Cochrane Headline outcomes only
  RR 5.35 [1.29, 22.11]
  2 studies · 48 participants
  Low

FLUPHENAZINE (ORAL) vs AMISULPRIDE

It is very uncertain whether FLUPHENAZINE (ORAL) changes adverse effects: Extrapyramidal effects ‐ concomitant… compared with AMISULPRIDE (very low certainty).

• Fluphenazine (oral) versus atypical antipsychotics for schizophrenia 2016 · Cochrane Headline outcomes only
  RR 7.82 [1.07, 57.26]
  1 study · 36 participants
  Very low

Intervention not reported

The intervention probably leads to higher freedom from AF/AFL/AT off antiarrhythmic medications > 3 months (moderate certainty).

• Concomitant atrial fibrillation surgery for people undergoing cardiac surgery 2016 · Cochrane Headline outcomes only
  RR 2.04 [1.63, 2.55]
  8 studies · 649 participants
  Moderate

CBT vs usual care

• Cognitive behavioural therapy (CBT) for adults and adolescents with asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 23 participants
  Low

Paracetamol 500 mg to 650 mg vs placebo

• Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Paracetamol 1000 mg vs placebo

• Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Ketoprofen 25 mg vs placebo

• Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Moderate

Dexketoprofen 25 mg plus tramadol 75 mg vs placebo

• Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Moderate

Dexketoprofen 25 mg plus tramadol 75 mg vs placebo

• Single fixed‐dose oral dexketoprofen plus tramadol for acute postoperative pain in adults 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low

Experimental chewing adjuncts (bite wafers or chewing gum) vs No chewing gum, placebo, or control (no adjunct)

• Non‐pharmacological interventions for alleviating pain during orthodontic treatment 2016 · Cochrane All outcomes

  24 hours to 1 week
  Benson 2012 (57 participants): no statistically significant difference in analgesic consumption at 24 hours (P = 0.903) or one week (P = 0.104).
  1 study · 57 participants
  GRADE not reported

SSRIs or SNRIs vs amitriptyline

The review found no eligible studies for this question.

• Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found