Proportion of participants achieving a 50% reduction in disease severity · chronic palmoplantar pustulosis
Alitretinoin showed no clear difference in proportion of participants achieving a 50% reduction in disease… compared with placebo (moderate certainty).
1 finding from 1 review
Proportion of participants without relapse in the long term ‐ not reported · chronic palmoplantar pustulosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis
Alitretinoin showed no clear difference in proportion of participants with adverse effects ‐ measured over 24… compared with placebo (moderate certainty).
1 finding from 1 review
Ease of compliance to an intervention or a treatment ‐ not reported · chronic palmoplantar pustulosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema
Alteplase showed no clear difference in overall treatment failure, including mortality, thoracic surgery or… compared with urokinase (low certainty).
1 finding from 1 review
Overall treatment failure, including mortality, thoracic surgery or referral for further fibrinolytic therapy · adult parapneumonic effusions and empyema
Streptokinase showed no clear difference in overall treatment failure, including mortality, thoracic surgery or… compared with urokinase (low certainty).
1 finding from 1 review
Minor adverse events
1 finding from 1 review
Intervention not reported
Mean total blood loss (mL: antifibrinolytics vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Number of participants receiving transfusion with allogeneic blood: antifibrinolytics vs placebo · children undergoing surgery for scoliosis
It is very uncertain whether the intervention changes number of participants receiving transfusion with allogeneic blood:… (very low certainty).
1 finding from 1 review
Intervention not reported
Number of participants receiving transfusion with allogeneic blood: aminocaproic acid vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Mean total blood transfused (mL): antifibrinolytics vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Mean total blood transfused (mL): aminocaproic acid vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Mean total blood loss (mL): aminocaproic acid vs placebo · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Mean total blood loss (mL): aminocaproic acid vs tranexamic acid · children undergoing surgery for scoliosis
1 finding from 1 review
Intervention not reported
Number of participants receiving blood transfusion: antifibrinolytics vs placebo · children undergoing surgery for scoliosis
It is very uncertain whether the intervention changes number of participants receiving blood transfusion:… (very low certainty).
1 finding from 1 review
Intervention not reported
Number of participants receiving blood transfusion: aminocaproic acid vs placebo · children undergoing surgery for scoliosis
It is very uncertain whether the intervention changes number of participants receiving blood transfusion: aminocaproic… (very low certainty).
1 finding from 1 review
Acute postoperative pain 0 to 6 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
Acute postoperative pain at 12 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
Acute postoperative pain at 24 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing brain surgery
1 finding from 1 review