Findings

What do systematic reviews say?

920 questions · 964 findings · 153 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 215 · 22.3%GRADE not reported 85 · 8.8%Very low 241 · 25%Low 260 · 27%Moderate 135 · 14%High 28 · 2.9%

Lithium vs carbamazepine

Efficacy: response (continuous) YMRS/BPRS change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 102 participants
Very low

Lithium vs carbamazepine

Efficacy: response (continuous) CGI change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Moderate

Lithium vs QUETIAPINE

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 359 participants
Low

Lithium vs OLANZAPINE

Efficacy: response (continuous) CGI severity score at end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 210 participants
Low

Lithium vs chlorpromazine

Efficacy: response (continuous) change in BPRS (total) from baseline to end of study ‐all data · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 284 participants
Very low

Lithium vs haloperidol

Efficacy: response (continuous) change in BPRS (total) from baseline to end of study ‐all data · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 80 participants
Very low

Lithium vs Zuclopenthixol (Cis Z/Trans E isomer)

Efficacy: response (continuous) change in BPRS (total) from baseline to end of study ‐all data · acute mania

The review found no eligible studies for this question.

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lithium vs RISPERIDONE

Efficacy: response (continuous) YMRS/MRS change at the end of the study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 241 participants
Low

Lithium vs ARIPIPRAZOLE

Efficacy: response (continuous) YMRS change by ≥ 50% at end of study · acute mania

Lithium showed no clear difference in efficacy: response (continuous) YMRS change by ≥ 50% at end of study compared with aripiprazole (moderate certainty).

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
OR 0.96 [0.62, 1.51]
1 study · 309 participants
Moderate

Lithium vs topiramate

Efficacy: response (continuous) YMRS change by ≥ 50% at end of study · acute mania

The review found no eligible studies for this question.

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lithium vs clonazepam

Efficacy: response (continuous) CGI change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 41 participants
Moderate

Lithium vs ECT

Efficacy: response (continuous) MRS mean change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Lithium vs all antimanic agents

Efficacy: response (continuous) YMRS/BPRS change from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 2410 participants
Low

Lithium vs valproate

Efficacy: response (continuous) Change in YMRS (ITT‐LOCF) from baseline to end of study · acute mania

1 finding from 1 review

Lithium for acute mania 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 398 participants
Very low

Physical therapy interventions vs usual care or no treatment

Functional ability · people with stroke and urinary incontinence

Physical therapy interventions probably leads to higher functional ability: mean Barthel score (continuous variables) compared with usual care or no treatment (moderate certainty).

1 finding from 1 review

Interventions for treating urinary incontinence after stroke in adults 2019 · Cochrane Headline outcomes only
MD 8.97 [1.27, 16.68]
81 participants
Moderate

Summary of findings: Iron vs placebo

Change in quality of life (continuous measure) · patients with restless legs syndrome

1 finding from 1 review

Iron for the treatment of restless legs syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 128 participants
Very low

Motivational interviewing/mindfulness and cognitive skills vs relaxation training

Drug abuse Self reported use of marijuana · drug‐using offenders with co‐occurring mental health problems

1 finding from 1 review

Interventions for drug‐using offenders with co‐occurring mental health problems 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 181 participants
Moderate

Supplemental IV crystalloid vs control IV crystalloid volume

Nausea · participants aged 6 months or older undergoing surgical procedures under general anaesthesia

Supplemental IV crystalloid probably leads to lower risk of PON, defined as the presence of subjective nausea, reported… compared with control IV crystalloid volume (moderate certainty).

1 finding from 1 review

Supplemental perioperative intravenous crystalloids for postoperative nausea and vomiting 2019 · Cochrane Headline outcomes only
RR 0.62 [0.51, 0.75]
18 studies · 1766 participants
Moderate

Combined oral contraceptive pill vs any other medical treatment

Self‐reported pain (dysmenorrhoea) at the end of treatment (continuous data): dysmenorrhoea at 6 months' · women with endometriosis

2 findings from 1 review

Oral contraceptives for pain associated with endometriosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low
Oral contraceptives for pain associated with endometriosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

Interventions targeting patients vs usual care or interventions of the same type

Observer‐based SDM measures · patients, including healthcare consumers and simulated patients

1 finding from 1 review

Interventions for increasing the use of shared decision making by healthcare professionals 2018 · Cochrane Headline outcomes only
no estimate extracted
424 participants
Very low