Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,248 questions in 108 reviews · Stroke

current versions
No studies 275 · 22%Ungraded 56 · 4.5%Very low 269 · 21.6%Low 349 · 28%Moderate 216 · 17.3%High 83 · 6.7%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Circuit class therapy vs other intervention
Independence in mobility Functional ambulation classification. Indicates need for assistance/not to safely mobilise · people with stroke
Circuit class therapy for improving mobility after stroke (2017) · Cochrane
no estimate extracted3 studies · 469 participantsModerate
Circuit class therapy vs other intervention
Physical ability Stroke Impact Scale. A self report of overall physical ability (subscale of total Impact) · people with stroke
Circuit class therapy for improving mobility after stroke (2017) · Cochrane
no estimate extracted2 studies · 437 participantsLow
Circuit class therapy vs other intervention
Adverse events (falls) from all available trials Counts of numbers of falls · people with stroke
Circuit class therapy for improving mobility after stroke (2017) · Cochrane
RD 0.038 studies · 815 participantsVery low
Virtual reality vs conventional therapy
Upper limb function · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted22 studies · 1038 participantsLow
Virtual reality vs conventional therapy
Quality of life · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted3 studies · 300 participantsLow
Virtual reality vs conventional therapy
Gait speed · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted6 studies · 139 participantsLow
Virtual reality vs conventional therapy
ADL outcome · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted10 studies · 466 participantsModerate
Virtual reality plus usual care vs usual care alone
Upper limb function · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted10 studies · 210 participantsLow
Virtual reality plus usual care vs usual care alone
Quality of life ‐ not measured in any of the studies · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extractedNRNo studies
Virtual reality plus usual care vs usual care alone
Gait speed · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted3 studies · 57 participantsLow
Virtual reality plus usual care vs usual care alone
Global motor function · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted3 studies · 43 participantsLow
Virtual reality plus usual care vs usual care alone
ADL outcome · people receiving stroke rehabilitation
Virtual reality for stroke rehabilitation (2017) · Cochrane
no estimate extracted8 studies · 153 participantsLow
Intervention NR
Proportion of stroke patients without clinical diagnosis of an anxiety disorder · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extracted1 study · 19 participantsVery low
Intervention NR
Proportion of stroke patients scoring outside anxiety range; or changes from baseline on an anxiety rating scale · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extracted3 studies · 196 participantsVery low
Intervention NR
Co‐morbid depression · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extracted2 studies · 175 participantsUngraded
Intervention NR
Quality of life ‐ not reported · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Social activities ‐ not reported · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Activities of daily living · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extracted1 study · 81 participantsVery low
Intervention NR
Principal caregiver burden ‐ not reported · stroke survivors with anxiety
Interventions for treating anxiety after stroke (2017) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Quality of life: Stroke Impact Scale (SIS) SIS measures quality of life across five domains: physical (strength, hand‐function, mobility, activities of daily living), emotion, memory, communication, social participation, plus 1 global question abo... · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Intervention NR
Quality of life: Stroke‐specific QoL Scale (SS QoL) The Stroke‐specific QoL Scale measures quality of life across 12 domains (49 items): self‐care, vision, language, mobility, work, upper extremity, thinking, personality, mood, family, social, and... · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 47 participantsVery low
Intervention NR
Balance: Berg Balance Scale (BBS) · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted2 studies · 69 participantsVery low
Intervention NR
Gait: Comfortable Gait Speed (CGS) Gait measured over 7 metres (3 repetitions; average time calculated) Baseline and post‐intervention · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Intervention NR
Depression: Geriatric Depression Scale (GDS15) A 15‐item self‐report assessment used to identify depression in the elderly. A yes/no response is required for each item (score 0 or 1). Cummulative score: 0‐4 normal, 5‐9 Mild depression, 10‐15 More ... · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Intervention NR
Anxiety: State Trait Anxiety (STAI‐Y1) A 40‐item, self‐report assessment of anxiety affect. State anxiety can be defined as fear, nervousness, discomfort, and the arousal of the autonomic nervous system induced temporarily by situations perceived ... · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Intervention NR
Anxiety: Trait Anxiety Inventory (STAI‐Y2) A 40‐item, self‐report assessment of anxiety affect. Trait anxiety can be defined as a relatively enduring disposition to feel stress, worry, and discomfort. Score 20‐80; higher scores suggest higher leve... · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 22 participantsVery low
Intervention NR
Disability: modified Rankin Scale (mRS) A measure of disability, with 6 categories: 0 (no symptoms), 1 (no significant disability), 2 (slight disability), 3 (moderate disability), 4 (moderately severe disability), 5 (severe disability), 6 (dead); ... · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extracted1 study · 47 participantsVery low
Intervention NR
Adverse events Post‐intervention · adults with stroke
Yoga for stroke rehabilitation (2017) · Cochrane
no estimate extractedNRVery low
Summary of findings: SLT vs no SLT (immediate outcome)
Functional communication · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.28 [0.06, 0.49]10 studies · 376 participantsModerate
Summary of findings: SLT vs no SLT (follow‐up at 6 months)
Expressive language: naming (6 months · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.073 studies · 111 participantsVery low
Summary of findings: SLT vs no SLT (follow‐up at 6 months)
Number of dropouts (for any reason) · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
OR 0.73 [0.38, 1.39]6 studies · 322 participantsModerate
Summary of findings: SLT vs social support and stimulation
Functional communication · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
no estimate extractedNRNo studies
Summary of findings: SLT vs social support and stimulation
Expressive language: naming · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 1.243 studies · 33 participantsVery low
Summary of findings: SLT vs social support and stimulation
Number of dropouts for any reason · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
OR 0.51 [0.32, 0.82]5 studies · 413 participantsLow
Summary of findings: SLT A vs SLT B
Functional communication · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
MD 11.75 [4.09, 19.4]2 studies · 84 participantsLow
Summary of findings: SLT A vs SLT B
Severity of impairment · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.38 [0.07, 0.69]5 studies · 187 participantsModerate
Summary of findings: SLT vs no SLT (immediate outcome)
Receptive language: auditory comprehension · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.069 studies · 399 participantsLow
Summary of findings: SLT vs no SLT (immediate outcome)
Receptive language: reading comprehension · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.29 [0.03, 0.55]8 studies · 253 participantsModerate
Summary of findings: SLT vs no SLT (immediate outcome)
Expressive language: naming · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.147 studies · 275 participantsLow
Summary of findings: SLT vs no SLT (immediate outcome)
Expressive language: general · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 1.28 [0.38, 2.19]7 studies · 248 participantsLow
Summary of findings: SLT vs no SLT (immediate outcome)
Expressive language: written · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.41 [0.14, 0.67]8 studies · 253 participantsModerate
Summary of findings: SLT vs no SLT (immediate outcome)
Number of dropouts (for any reason) · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
OR 0.89 [0.64, 1.25]13 studies · 921 participantsModerate
Summary of findings: SLT vs no SLT (follow‐up at 6 months)
Functional communication (6 months · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
SMD 0.192 studies · 111 participantsVery low
Summary of findings: SLT vs no SLT (follow‐up at 6 months)
Receptive language: auditory comprehension (6 months · adults with aphasia following stroke
Speech and language therapy for aphasia following stroke (2016) · Cochrane
MD 1.382 studies · 111 participantsVery low
Intervention NR
Subjective memory measures (immediate outcome) · patients with memory deficits following stroke
Cognitive rehabilitation for memory deficits after stroke (2016) · Cochrane
no estimate extracted7 studies · 215 participantsModerate
Intervention NR
Quality of life measures (long‐term outcome) · patients with memory deficits following stroke
Cognitive rehabilitation for memory deficits after stroke (2016) · Cochrane
no estimate extracted1 study · 134 participantsModerate
Intervention NR
Subjective memory measures (long‐term outcome) · patients with memory deficits following stroke
Cognitive rehabilitation for memory deficits after stroke (2016) · Cochrane
no estimate extracted3 studies · 149 participantsLow
Intervention NR
Objective memory measures (immediate outcome) ‐ comprehensive batteries · patients with memory deficits following stroke
Cognitive rehabilitation for memory deficits after stroke (2016) · Cochrane
no estimate extracted5 studies · 91 participantsVery low
Intervention NR
Objective memory measures (immediate outcome) ‐ verbal memory sub‐tests · patients with memory deficits following stroke
Cognitive rehabilitation for memory deficits after stroke (2016) · Cochrane
no estimate extracted5 studies · 266 participantsModerate
Intervention NR
Objective memory measures (long‐term outcome) ‐ comprehensive batteries · patients with memory deficits following stroke
Cognitive rehabilitation for memory deficits after stroke (2016) · Cochrane
no estimate extracted3 studies · 49 participantsLow