Cochrane · systematic review · CD000425
Speech and language therapy for aphasia following stroke
Brady, MC, Kelly, H, Godwin, J, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
15
No studies
1
Included studies
NR
No studies 1 · 6.3%Ungraded 0 · 0%Very low 4 · 25%Low 5 · 31.3%Moderate 6 · 37.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings: SLT versus no SLT (immediate outcome)
Population: adults with aphasia following stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional communication Summary of findings: SLT vs no SLT (immediate outcome) | SMD 0.28 [0.06, 0.49] | 10 studies · 376 participants | Moderate Downgraded: risk of bias |
Receptive language: auditory comprehension Summary of findings: SLT vs no SLT (immediate outcome) | SMD 0.06 | 9 studies · 399 participants | Low Downgraded: risk of bias, imprecision |
Receptive language: reading comprehension Summary of findings: SLT vs no SLT (immediate outcome) | SMD 0.29 [0.03, 0.55] | 8 studies · 253 participants | Moderate Downgraded: risk of bias |
Expressive language: naming Summary of findings: SLT vs no SLT (immediate outcome) | SMD 0.14 | 7 studies · 275 participants | Low Downgraded: risk of bias, imprecision |
Expressive language: general Summary of findings: SLT vs no SLT (immediate outcome) | SMD 1.28 [0.38, 2.19] | 7 studies · 248 participants | Low Downgraded: risk of bias, imprecision |
Expressive language: written Summary of findings: SLT vs no SLT (immediate outcome) | SMD 0.41 [0.14, 0.67] | 8 studies · 253 participants | Moderate Downgraded: risk of bias |
Number of dropouts (for any reason) Summary of findings: SLT vs no SLT (immediate outcome) | OR 0.89 [0.64, 1.25] | 13 studies · 921 participants | Moderate Downgraded: risk of bias |
Summary of findings: SLT versus no SLT (follow‐up at 6 months)
Population: adults with aphasia following stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional communication (6 months Summary of findings: SLT vs no SLT (follow‐up at 6 months) | SMD 0.19 | 2 studies · 111 participants | Very low Downgraded: risk of bias |
Receptive language: auditory comprehension (6 months Summary of findings: SLT vs no SLT (follow‐up at 6 months) | MD 1.38 | 2 studies · 111 participants | Very low Downgraded: risk of bias |
Expressive language: naming (6 months Summary of findings: SLT vs no SLT (follow‐up at 6 months) | SMD 0.07 | 3 studies · 111 participants | Very low Downgraded: risk of bias |
Number of dropouts (for any reason) Summary of findings: SLT vs no SLT (follow‐up at 6 months) | OR 0.73 [0.38, 1.39] | 6 studies · 322 participants | Moderate Downgraded: risk of bias |
Summary of findings: SLT versus social support and stimulation
Population: adults with aphasia following stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional communication Summary of findings: SLT vs social support and stimulation | no estimate extracted | NR | No studies |
Expressive language: naming Summary of findings: SLT vs social support and stimulation | SMD 1.24 | 3 studies · 33 participants | Very low Downgraded: risk of bias |
Number of dropouts for any reason Summary of findings: SLT vs social support and stimulation | OR 0.51 [0.32, 0.82] | 5 studies · 413 participants | Low Downgraded: risk of bias |
Summary of findings: SLT A versus SLT B for functional communications outcomes
Population: adults with aphasia following stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Functional communication Summary of findings: SLT A vs SLT B | MD 11.75 [4.09, 19.4] | 2 studies · 84 participants | Low Downgraded: risk of bias |
Summary of findings: SLT A versus SLT B for severity of impairment outcomes
Population: adults with aphasia following stroke
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severity of impairment Summary of findings: SLT A vs SLT B | SMD 0.38 [0.07, 0.69] | 5 studies · 187 participants | Moderate Downgraded: risk of bias |