Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Intervention not reported

Quality of life up to longest · non‐hospitalised adults with mild COVID‐19

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Thrombotic events at longest · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention showed no clear difference in thrombotic events at longest (moderate certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events at longest · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention showed no clear difference in serious adverse events at longest (low certainty).

1 finding from 1 review

Intervention not reported

Major bleeding events at longest · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention probably leads to higher major bleeding events at longest (moderate certainty).

1 finding from 1 review

Intervention not reported

Episodes of bradycardia, defined as a fall in heart rate of more than 30% below the baseline or less than 100 beats per minute for 10 seconds or longer, occurring during the procedure · Procedural pain in neonates

The review found no eligible studies for this question.

1 finding from 1 review

Adenoidectomy and unilateral ventilation tube vs unilateral ventilation tube only

Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether adenoidectomy and unilateral ventilation tube changes presence or persistence of OME (3 years ‐ long‐term) № of… compared with unilateral ventilation tube only (very low certainty).

1 finding from 1 review

Adenoidectomy and ventilation tubes vs watchful waiting

Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether adenoidectomy and ventilation tubes changes presence/persistence of OME (at 2 years ‐ long‐term) № of… compared with no treatment/watchful waiting (very low certainty).

1 finding from 1 review

Intervention not reported

Quality of life up to 28 days and longest · hospitalized people with mild to moderate symptomatic COVID‐19 (WHO scale 2 to 4) with severe comorbidities

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

All initial symptoms resolved at 28 days, and up to the longest · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life up to 28 days and longest · unvaccinated, non‐hospitalized people with mild symptomatic COVID‐19 (WHO scale 2 to 3) at high risk for progression to severe disease

The review found no eligible studies for this question.

1 finding from 1 review