Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,234 questions · 3,357 findings · 396 reviews

No studies found 803 · 23.9%GRADE not reported 270 · 8%Very low 757 · 22.5%Low 859 · 25.6%Moderate 486 · 14.5%High 182 · 5.4%

Low‐molecular‐weight heparins or heparinoids vs unfractionated heparin

Death from all causes during treatment (range 6 days to 16 days) · acute ischaemic stroke

Low‐molecular‐weight heparins or heparinoids showed no clear difference in death from all causes during treatment (range 6 days to 16 days) compared with unfractionated heparin (low certainty).

1 finding from 1 review

Low‐molecular‐weight heparins or heparinoids vs unfractionated heparin

Death from all causes during · acute ischaemic stroke

Low‐molecular‐weight heparins or heparinoids showed no clear difference in death from all causes during compared with unfractionated heparin (low certainty).

1 finding from 1 review

Low‐molecular‐weight heparins or heparinoids vs unfractionated heparin

Deep vein thrombosis · acute ischaemic stroke

Low‐molecular‐weight heparins or heparinoids may leads to lower deep vein thrombosis during treatment period (range 6 days to 16 days) compared with unfractionated heparin (low certainty).

1 finding from 1 review

Low‐molecular‐weight heparins or heparinoids vs unfractionated heparin

Pulmonary embolism · acute ischaemic stroke

Low‐molecular‐weight heparins or heparinoids showed no clear difference in pulmonary embolism during treatment period (range 6 days to 16 days) compared with unfractionated heparin (low certainty).

1 finding from 1 review

Low‐molecular‐weight heparins or heparinoids vs unfractionated heparin

Symptomatic intracranial haemorrhage/haemorrhagic transformation of the cerebral infarct during treatment period (range 6 days to 16 days)⁹ · acute ischaemic stroke

Low‐molecular‐weight heparins or heparinoids showed no clear difference in symptomatic intracranial haemorrhage/haemorrhagic transformation of… compared with unfractionated heparin (low certainty).

1 finding from 1 review

Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms

Exacerbations · people with asthma

Tailored interventions based on sputum eosinophils probably leads to lower number of participants who had one or more exacerbations over the… compared with tailored interventions based on clinical symptoms (moderate certainty).

1 finding from 1 review

Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms

Hospital admissions · people with asthma

Tailored interventions based on sputum eosinophils probably leads to lower hospitalisations compared with tailored interventions based on clinical symptoms (moderate certainty).

1 finding from 1 review

Gestrinone vs danazol

Side effects ‐ hot flushes · women with symptomatic endometriosis

It is very uncertain whether gestrinone changes side effects: hot flushes compared with danazol (very low certainty).

1 finding from 1 review

Gestrinone vs leuprolin

Percentage days bleeding or spotting (questionnaire) · women with symptomatic endometriosis

Gestrinone may leads to higher spotting or bleeding compared with leuprolin (low certainty).

1 finding from 1 review