Findings

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Evidence found and GRADE certainty

4,534 questions · 5,247 findings · 456 reviews

No studies found 1,142 · 21.8%GRADE not reported 1,503 · 28.6%Very low 1,040 · 19.8%Low 869 · 16.6%Moderate 554 · 10.6%High 139 · 2.6%

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Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Plaque · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

Triclosan/copolymer-containing fluoride toothpaste probably leads to lower plaque at 6 to 7 months (Quigley-Hein Plaque Index, 0 to 5 scale) compared with fluoride toothpaste without triclosan (moderate certainty).

3 findings from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Oral cancer mortality (disease-specific) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

Visual screening (oral visual inspection) by trained health workers showed no clear difference in oral cancer mortality (disease-specific) compared with no screening (low certainty).

2 findings from 1 review

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

Gingivitis · Adults, 16 years and older (dentate)

Interdental brushing plus toothbrushing may leads to lower gingivitis (bleeding and gingival indices; standardised across… compared with flossing plus toothbrushing (low certainty).

2 findings from 1 review · compare the 2 reviews

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Dental caries: prevalence of root caries · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

Triclosan/copolymer-containing fluoride toothpaste probably leads to lower root caries at 36 months (Katz Root Caries Index) compared with fluoride toothpaste without triclosan (moderate certainty).

1 finding from 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Gingival bleeding (various bleeding indices) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

Triclosan/copolymer-containing fluoride toothpaste probably leads to lower gingival bleeding at 6 to 7 months (Gingivitis Severity Index,… compared with fluoride toothpaste without triclosan (moderate certainty).

2 findings from 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Gingivitis · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

Triclosan/copolymer-containing fluoride toothpaste probably leads to lower gingivitis at 6 to 9 months (Loe-Silness Gingival Index, 0 to 3 scale) compared with fluoride toothpaste without triclosan (moderate certainty).

1 finding from 1 review

Orthodontic distalising appliance (intraoral or extraoral) vs no intervention

Duration of treatment · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

The review found no eligible studies for this question.

1 finding from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Costs · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…
1 finding from 1 review
  • Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes
    9 years (three cycles)
    The costs associated with the screening programme were reported after three cycles (nine years) (Subramanian 2009) (Additional Table 8). The benefit produced by a screen was 269.31 life-years saved per 100,000 for all…
    1 study
    GRADE not reported

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Change in oral health knowledge and skills · Children aged 4 to 12 years attending primary school
1 finding from 1 review

Orthodontic distalising appliance (intraoral or extraoral) vs no intervention

Movement of upper incisor teeth (mm) · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…
1 finding from 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Coronal caries increment · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

Triclosan/copolymer-containing fluoride toothpaste showed no clear difference in coronal caries increment at 30 to 36 months (decayed filled teeth,… compared with fluoride toothpaste without triclosan (high certainty).

2 findings from 1 review

Intraoral distalising appliance vs Headgear (extraoral appliance)

Movement of upper first molars (mm) · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

It is very uncertain whether intraoral distalising appliance changes movement of upper first molars (mm) compared with headgear (extraoral appliance) (very low certainty).

1 finding from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Harms of screening (false-positive/false-negative outcomes) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

The review found no eligible studies for this question.

1 finding from 1 review

Fluoride varnish vs placebo or no treatment

Adverse effects / specific side effects (oral allergic reactions, mucosal irritation, adverse symptoms such as nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
1 finding from 1 review

Interdental brushing plus toothbrushing vs Flossing plus toothbrushing

Plaque · Adults, 16 years and older (dentate)

Interdental brushing plus toothbrushing showed no clear difference in plaque (plaque indices; standardised across indices) compared with flossing plus toothbrushing (low certainty).

2 findings from 1 review · compare the 2 reviews