Question · asked by 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan: Plaque

Population
Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults, with children in 2 studies
Intervention
Triclosan/copolymer-containing fluoride toothpaste
Comparison
Fluoride toothpaste without triclosan
Outcome
Plaque

Triclosan/copolymer-containing fluoride toothpaste probably leads to lower plaque at 6 to 7 months (Quigley-Hein Plaque Index, 0 to 5 scale) compared with fluoride toothpaste without triclosan (moderate certainty).

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 0 · 0%
FindingEffectStudiesGRADE certainty
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan
Plaque at 6 to 7 months (Quigley-Hein Plaque Index, 0 to 5 scale) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 7 months
Triclosan/copolymer-containing fluoride toothpaste probably leads to lower plaque at 6 to 7 months (Quigley-Hein Plaque Index, 0 to 5 scale) compared with fluoride toothpaste without triclosan (moderate certainty).
Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane All outcomes
MD -0.47 [-0.60, -0.34]20 studies · 2675 participantsModerate
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan
Plaque severity at 6 to 7 months (Plaque Severity Index, proportion of surfaces scoring > 3 on the Quigley-Hein Plaque Index) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 7 months
Triclosan/copolymer-containing fluoride toothpaste probably leads to lower plaque severity at 6 to 7 months (Plaque Severity Index, proportion… compared with fluoride toothpaste without triclosan (moderate certainty).
Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane All outcomes
MD -0.15 [-0.20, -0.10]13 studies · 1850 participantsModerate
Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan
Plaque at 6 to 7 months (Loe-Silness Plaque Index) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in… · 6 to 7 months
Triclosan/copolymer-containing fluoride toothpaste led to lower plaque at 6 to 7 months (Loe-Silness Plaque Index) compared with fluoride toothpaste without triclosan; GRADE not reported.
Triclosan/copolymer containing toothpastes for oral health (2013) · Cochrane All outcomes
MD -0.05 [-0.10, -0.01]2 studies · 148 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Triclosan/copolymer containing toothpastes for oral health
2013 · Cochrane All outcomes
2013-08Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.