Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

948 questions · 998 findings · 100 reviews · Headline outcomes only

No studies found 233 · 23.3%GRADE not reported 40 · 4%Very low 203 · 20.3%Low 271 · 27.2%Moderate 176 · 17.6%High 75 · 7.5%

Vitamin D plus calcium vs calcium

Healing of rickets (number) Definition: normal alkaline phosphatase and bone radiograph

It is very uncertain whether vitamin D plus calcium changes healing of rickets (number) Definition: normal alkaline phosphatase… compared with calcium (very low certainty).

1 finding from 1 review

Vitamin D plus calcium vs calcium

Adverse events (number) Asymptomatic hypercalcaemia and hypercalciuria

It is very uncertain whether vitamin D plus calcium changes adverse events (number) Asymptomatic hypercalcaemia and hypercalciuria compared with calcium (very low certainty).

1 finding from 1 review

Vitamin A vs no supplementation

Chronic lung disease · promoting growth and development in very low birth weight infants receiving human milk

Supplemental vitamin A showed no clear difference in chronic lung disease (oxygen use at 28 days in survivors) compared with no supplementation (moderate certainty).

2 findings from 1 review