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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

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No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

Light-cured resin-modified glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    Fricker 1997 was a three-arm split-mouth trial that included a light-cured resin-modified glass ionomer arm (compared with light-cured compomer and chemically cured glass ionomer). Failure rates were reported but not…
    1 study
    GRADE not reported

Chemically cured zinc phosphate cement vs Glass ionomer cement (GIC)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    No meta-analysis (band failure not reported on a per-patient basis). Durning 1989 (69 participants): at ~12 months failure rate 34.78% (zinc phosphate) vs 26% (glass ionomer), P > 0.05; mean survival time 470.9 vs…
    4 studies
    GRADE not reported

Chemically cured glass ionomer cement vs Chemically cured glass phosphonate

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    Clark 2003: failure rates presented per adhesive group by number of bands failing (overall proportion of band failure 0.048 for each material); no per-patient failure data. Low band failure rates; insufficient evidence…
    1 study
    GRADE not reported

Chemically cured glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin)

Band failure (band adhesive loosening) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
  • Adhesives for fixed orthodontic bands 2016 · Cochrane All outcomes
    Approximately 12 months (to end of treatment)
    No meta-analysis. Fricker 1997: failure data not presented in an analysable format (number of bands or failures per person not given). Gillgrass 2001 (98 participants; 140 band pairs): 4 single-band failures with…
    3 studies
    GRADE not reported

Anti‐D administration in pregnancy vs no treatment

Incidence of Rhesus D alloimmunisation during pregnancy · Rh‐negative women without anti‐D antibodies

Anti‐D administration in pregnancy showed no clear difference in incidence of Rhesus D alloimmunisation during pregnancy compared with no treatment (low certainty).

1 finding from 1 review

Anti‐D administration in pregnancy vs no treatment

Incidence of Rhesus D alloimmunisation postpartum (at birth of Rh‐positive infant and at · Rh‐negative women without anti‐D antibodies

Anti‐D administration in pregnancy showed no clear difference in incidence of Rhesus D alloimmunisation postpartum (at birth of… compared with no treatment (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects from chest radiographs · adults and children with clinical signs and symptoms of acute lower respiratory tract infection

The review found no eligible studies for this question.

1 finding from 1 review

Regional anaesthesia vs conventional pain control

Knee Society Score compared to preoperative value · people undergoing total knee replacement
2 findings from 1 review

9.5% adhesion HP strip vs HP strips

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 9.5% adhesion HP strip changes tooth whitening - assessed by the dentist compared with 10% HP strip (very low certainty).

1 finding from 1 review

Annual chest x‐ray screening vs usual care (no regular screening)

Mortality: lung cancer · Patients with lung cancer

Annual chest x‐ray screening showed no clear difference in lung cancer mortality at 6 years of compared with usual care (no regular screening) (high certainty).

2 findings from 1 review