Vomiting · lower gastrointestinal surgery
Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in vomiting compared with later commencement (low certainty).
1 finding from 1 review
Nausea · lower gastrointestinal surgery
Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in nausea compared with later commencement (low certainty).
1 finding from 1 review
Nausea and vomiting · lower gastrointestinal surgery
It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes nausea and vomiting compared with later commencement (very low certainty).
1 finding from 1 review
Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm or low birth weight infants with PDA
Early paracetamol may leads to lower failure of PDA closure after first course of treatment (by… compared with placebo/no intervention (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm or low birth weight infants with PDA
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm or low birth weight infants with PDA
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality ( · small asymptomatic AAA
Early open repair leads to lower mortality ( compared with ultrasound surveillance (high certainty).
1 finding from 1 review
Costs · small asymptomatic AAA
Early open repair showed no clear difference in costs (per participant) ( compared with ultrasound surveillance (moderate certainty).
1 finding from 1 review
QoLc ( · small asymptomatic AAA
1 finding from 1 review
Aneurysm rupture ( · small asymptomatic AAA
1 finding from 1 review
Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
Early-childhood oral hygiene and dietary habits show inconsistent associations with permanent-teeth caries, often losing significance after adjustment for past caries (2 studies; not pooled; not GRADE-rated).
1 finding from 1 review
All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis
Early amniocentesis showed no clear difference in all known pregnancy loss (including termination of pregnancy) compared with transabdominal chorionic villus sampling (low certainty).
1 finding from 1 review
Miscarriage · prenatal diagnosis
Early amniocentesis probably leads to higher spontaneous miscarriage compared with transabdominal chorionic villus sampling (moderate certainty).
1 finding from 1 review
Sampling failure · prenatal diagnosis
Early amniocentesis showed no clear difference in sampling failure compared with transabdominal chorionic villus sampling (low certainty).
1 finding from 1 review
Laboratory failure · prenatal diagnosis
Early amniocentesis showed no clear difference in laboratory failure compared with transabdominal chorionic villus sampling (low certainty).
1 finding from 1 review
Known false negative after birth · prenatal diagnosis
1 finding from 1 review
Delivery before 33 weeks · prenatal diagnosis
Early amniocentesis showed no clear difference in delivery before 33 weeks compared with transabdominal chorionic villus sampling (low certainty).
1 finding from 1 review
Anomalies (all recorded) · prenatal diagnosis
It is very uncertain whether early amniocentesis changes anomalies (all recorded) compared with transabdominal chorionic villus sampling (very low certainty).
1 finding from 1 review
Early childhood caries (ECC) · Healthy children under 6 years of age (6 months to 6 years); preschool children
After excluding an extreme outlier (Alhabdan 2018), the association between low brushing frequency and ECC remained statistically significant (pooled OR approximately 2.0, p=0.003; I2=87.5%); the exact estimate and its CI were not reported; ungraded.
2 findings from 1 review
Early childhood caries (ECC) · Children younger than 71 months (under 6 years)
Breastfeeding for more than 12 months is associated with higher ECC prevalence (low certainty).
1 finding from 1 review
OR 1.86 [1.48, 2.35]
13 studies
Low