Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,187 questions · 1,233 findings · 137 reviews

No studies found 190 · 15.4%GRADE not reported 57 · 4.6%Very low 241 · 19.5%Low 323 · 26.2%Moderate 315 · 25.5%High 107 · 8.7%

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

Maternal death · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B1: Maternal death – all women compared with single course (low certainty).

1 finding from 1 review

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids vs single course

B2: Maternal sepsis – an all women · the woman

Summary of findings table ‐ Repeat dose(s) of prenatal corticosteroids showed no clear difference in B2: Maternal sepsis – an all women compared with single course (moderate certainty).

1 finding from 1 review

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs beclomethasone

Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma

Effects of different inhaled corticosteroids on growth in children… may leads to higher linear growth velocity (cm/year) compared with beclomethasone (low certainty).

1 finding from 1 review

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs budesonide

Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma

It is very uncertain whether effects of different inhaled corticosteroids on growth in children… changes linear growth velocity (cm/year) compared with budesonide (very low certainty).

1 finding from 1 review

Effects of different inhaled corticosteroids on growth in children with persistent asthma: fluticasone vs budesonide

Change in height · children up to 18 years of age with persistent asthma

Effects of different inhaled corticosteroids on growth in children… probably leads to higher change in height (cm) over a period of time compared with budesonide (moderate certainty).

1 finding from 1 review

Tacrolimus 0.03% vs corticosteroids

Physician's assessment of global response of improvement, clear or excellent ‐ 6 weeks · people with atopic dermatitis

Tacrolimus 0.03% probably leads to higher physician's assessment of global response of improvement, clear or… compared with corticosteroids (moderate certainty).

4 findings from 1 review
Show 1 more finding

Iontophoretically applied corticosteroids

Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

The review found no eligible studies for this question.

1 finding from 1 review

Strategies to increase use of antenatal corticosteroids vs usual care

Perinatal mortality · women at risk of preterm birth

Strategies to increase use of antenatal corticosteroids probably leads to higher perinatal death (at population level) compared with routine (usual) care (moderate certainty).

1 finding from 1 review

Strategies to increase use of antenatal corticosteroids vs usual care

Neonatal death (death within the first 28 days of life) · women at risk of preterm birth

Strategies to increase use of antenatal corticosteroids probably leads to higher neonatal death before 28 days (at population level) compared with routine (usual) care (moderate certainty).

1 finding from 1 review

Strategies to increase use of antenatal corticosteroids vs usual care

Stillbirth · women at risk of preterm birth

Strategies to increase use of antenatal corticosteroids probably leads to higher stillbirth (at population level) compared with routine (usual) care (moderate certainty).

1 finding from 1 review

Strategies to increase use of antenatal corticosteroids vs usual care

Appropriate ACS treatment (women) · women at risk of preterm birth

Strategies to increase use of antenatal corticosteroids may leads to higher appropriate ACS treatment (women) compared with routine (usual) care (low certainty).

1 finding from 1 review

Strategies to increase use of antenatal corticosteroids vs usual care

Inappropriate ACS treatment (women) · women at risk of preterm birth

Strategies to increase use of antenatal corticosteroids may leads to higher inappropriate ACS treatment (women) compared with routine (usual) care (low certainty).

1 finding from 1 review