Proportion of participants who required further glaucoma surgery, including laser · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
Cataract surgery with Hydrus microstent may leads to lower proportion of participants who required further glaucoma surgery,… compared with cataract surgery alone (low certainty).
1 finding from 1 review
All‐cause mortality within 30 days of surgery · people with a low platelet count
It is very uncertain whether prophylactic platelet transfusion prior to surgery changes all‐cause mortality within 30 days of surgery compared with no prophylactic platelet transfusion prior to surgery (very low certainty).
1 finding from 1 review
Mortality secondary to bleeding within 30 days of surgery – not reported · people with a low platelet count
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality secondary to thromboembolism within 30 days of surgery – not reported · people with a low platelet count
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality secondary to infection within 30 days of surgery – not reported · people with a low platelet count
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with major bleeding within 7 days of surgery (surgical site bleeding requiring a second intervention or reoperation or surgical site bleeding that causes a haematoma or haemarthrosis of sufficient size to delay mobilisation ... · people with a low platelet count
It is very uncertain whether prophylactic platelet transfusion prior to surgery changes number of participants with major bleeding within 7 days of surgery… compared with no prophylactic platelet transfusion prior to surgery (very low certainty).
1 finding from 1 review
Number of participants with minor procedure‐related bleeding within 7 days of surgery · people with a low platelet count
It is very uncertain whether prophylactic platelet transfusion prior to surgery changes the number of participants with minor procedure‐related bleeding… compared with no prophylactic platelet transfusion prior to surgery (very low certainty).
1 finding from 1 review
Serious adverse events (surgery‐related adverse effects within 30 days) · people with a low platelet count
1 finding from 1 review
1‐Year radiosurgery‐targeted lesion controlNo. of participants: 602(4 RCTs) · patients with newly diagnosed multiple brain metastases
Radiosurgery alone leads to higher 1‐Year radiosurgery‐targeted lesion controlNo. of participants:… compared with WBRT and radiosurgery (high certainty).
1 finding from 1 review
HR 2.73 [1.87, 3.99]
Studies not reported
High
Surgically‐related severe adverse effects (grade 3+) ‐ stoma formation (within 30 days of surgery) · women with advanced ovarian epithelial cancer
Neoadjuvant chemotherapy prior to interval surgery (NACT) probably leads to lower surgically‐related severe adverse effects (grade 3+) ‐ stoma… compared with surgery followed by chemotherapy (PDS) (moderate certainty).
1 finding from 1 review
Surgically‐related severe adverse effects (grade 3+) ‐ bowel resection (within 30 days of surgery) · women with advanced ovarian epithelial cancer
Neoadjuvant chemotherapy prior to interval surgery (NACT) probably leads to lower surgically‐related severe adverse effects (grade 3+) ‐ bowel… compared with surgery followed by chemotherapy (PDS) (moderate certainty).
1 finding from 1 review
Surgically‐related severe adverse effects (grade 3+) ‐ postoperative G3+ events (within 30 days of surgery) · women with advanced ovarian epithelial cancer
Neoadjuvant chemotherapy prior to interval surgery (NACT) probably leads to lower surgically‐related severe adverse effects (grade 3+) ‐ postoperative… compared with surgery followed by chemotherapy (PDS) (moderate certainty).
1 finding from 1 review
Surgically‐related postoperative mortality (28 days to 6 months of surgery4) · women with advanced ovarian epithelial cancer
Neoadjuvant chemotherapy prior to interval surgery (NACT) leads to lower surgically‐related postoperative mortality (28 days to 6 months of… compared with surgery followed by chemotherapy (PDS) (high certainty).
1 finding from 1 review
Complications of surgery (2–10 years) · people with non‐severe primary valvular incompetence
1 finding from 1 review
Clinical changes (CEAP classification scoring for clinical outcomes after surgery) (3 years) · people with non‐severe primary valvular incompetence
1 finding from 1 review
Repeat surgery (or pessary) for recurrent prolapse · women undergoing pelvic organ prolapse surgery
Pelvic floor muscle training before and after prolapse surgery showed no clear difference in repeat surgery (or pessary) for recurrent prolapse compared with no training (low certainty).
1 finding from 1 review
Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Proportion using one or more medications at one year after surgery Number of participants · patients with eyes with cataract and glaucoma
Combined surgery may leads to lower proportion using one or more medications at one year after surgery… compared with phacoemulsification alone (low certainty).
1 finding from 1 review
All‐cause mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery
It is very uncertain whether surgery changes all‐cause mortality at maximal compared with radiofrequency ablation (very low certainty).
1 finding from 1 review
Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma eligible for surgery
Surgery may leads to lower cancer‐related mortality at maximal compared with radiofrequency ablation (low certainty).
1 finding from 1 review