Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

62 questions · 63 findings · 5 reviews · Pain, Palliative and Supportive Care

No studies found 3 · 4.8%GRADE not reported 2 · 3.2%Very low 12 · 19%Low 3 · 4.8%Moderate 19 · 30.2%High 24 · 38.1%

Pregabalin vs placebo at end of treatment

Patient Global Impression of Change much or very much improved · patients with fibromyalgia

Pregabalin leads to higher patient Global Impression of Change of 'much' or 'very much' improved compared with placebo at end of treatment (high certainty).

1 finding from 1 review

Pregabalin vs placebo at end of treatment

Withdrawals due to adverse events · patients with fibromyalgia

Pregabalin leads to higher withdrawal due to adverse events compared with placebo at end of treatment (high certainty).

1 finding from 1 review

Pregabalin vs placebo at end of treatment

Serious adverse events · patients with fibromyalgia

Pregabalin showed no clear difference in serious adverse events compared with placebo at end of treatment (moderate certainty).

1 finding from 1 review