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What do systematic reviews say?

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Evidence found and GRADE certainty

130 questions · 155 findings · 13 reviews

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No studies found 34 · 21.9%GRADE not reported 13 · 8.4%Very low 35 · 22.6%Low 47 · 30.3%Moderate 23 · 14.8%High 3 · 1.9%

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

All‐cause mortality · post‐exacerbation COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation showed no clear difference in all‐cause mortality compared with standard treatment following a severe exacerbation (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

Change in arterial partial pressure of carbon dioxide · stable COPD
2 findings from 1 review

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

Change in the health‐related quality of life · stable COPD
2 findings from 1 review

Intravenous magnesium sulfate + standard care vs placebo + standard care

Proportion of people requiring non‐invasive ventilation · acute exacerbations of chronic obstructive pulmonary disease

It is very uncertain whether intravenous magnesium sulfate + standard care changes proportion of people requiring non‐invasive ventilation compared with placebo + standard care (very low certainty).

1 finding from 1 review

Non‐invasive ventilation vs supplemental oxygen or no treatment

Need for mechanical ventilation · patients with the management of transient tachypnea of the newborn

It is very uncertain whether non‐invasive respiratory support changes need for mechanical ventilation compared with supplemental oxygen or no treatment (very low certainty).

1 finding from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Cardiovascular mortality

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Serious adverse events

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Quality of sleep

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Quality of life

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

All‐cause mortality

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs bilevel ventilation

Time to life‐saving cardiovascular intervention

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Cardiovascular mortality

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Serious adverse events

The review found no eligible studies for this question.

2 findings from 1 review

Adaptive servo ventilation (ASV) vs continuous positive airway pressure (CPAP)

Quality of sleep

The review found no eligible studies for this question.

2 findings from 1 review