Question · asked by 1 review

Intravenous magnesium sulfate + standard care vs placebo + standard care: Proportion of people requiring non‐invasive ventilation

It is very uncertain whether intravenous magnesium sulfate + standard care changes proportion of people requiring non‐invasive ventilation compared with placebo + standard care (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Intravenous magnesium sulfate + standard care vs placebo + standard care
Proportion of people requiring non‐invasive ventilation · acute exacerbations of chronic obstructive pulmonary disease
It is very uncertain whether intravenous magnesium sulfate + standard care changes proportion of people requiring non‐invasive ventilation compared with placebo + standard care (very low certainty).
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease (2022) · Cochrane Headline outcomes only
OR 0.74 [0.31, 1.75]2 studies · 107 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.