Cochrane · systematic review · CD013231

Non‐invasive respiratory support for the management of transient tachypnea of the newborn

Moresco, L, Romantsik, O, Calevo, MG, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 18.2%Very low 9 · 81.8%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Non‐invasive respiratory support versus supplemental oxygen or no treatment for the management of transient tachypnea of the newborn

Population: patients with the management of transient tachypnea of the newborn
4 questions
OutcomeEffectEvidenceStatus / GRADE
Need for mechanical ventilation
Non‐invasive respiratory support vs supplemental oxygen or no treatment
RR 0.3 [0.01, 6.99]1 study · 64 participantsVery low
Downgraded: risk of bias
All‐cause mortality
Non‐invasive respiratory support vs supplemental oxygen or no treatment
RR 0.3 [0.01, 6.99]1 study · 64 participantsVery low
Downgraded: risk of bias
Duration of hospital stay
Non‐invasive respiratory support vs supplemental oxygen or no treatment
no estimate extracted1 study · 64 participantsVery low
Downgraded: risk of bias
Duration of tachypnea, defined as hours with respiratory rate greater than 60 breaths per minute
Non‐invasive respiratory support vs supplemental oxygen or no treatment
no estimate extracted1 study · 64 participantsVery low
Downgraded: risk of bias

CPAP versus nasal ventilation (NIPPV or NHFV) for the management of transient tachypnea of the newborn

Population: patients with the management of transient tachypnea of the newborn
7 questions
OutcomeEffectEvidenceStatus / GRADE
Need for mechanical ventilation ‒NIPPV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
RR 4 [0.49, 32.72]1 study · 40 participantsVery low
Downgraded: risk of bias
Need for mechanical ventilation ‒NHFV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
no estimate extracted1 study · 40 participantsUngraded
Pneumothorax ‒NIPPV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
RR 1 [0.07, 14.9]1 study · 40 participantsVery low
Downgraded: risk of bias
Pneumothorax ‒NHFV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
no estimate extracted1 study · 40 participantsUngraded
Duration of tachypnea, defined as hours with respiratory rate greater than 60 breaths per minute ‒NIPPV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias
Duration of tachypnea, defined as hours with respiratory rate greater than 60 breaths per minute ‒NHFV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Duration of hospital stay ‒NIPPV versus CPAP
CPAP vs nasal ventilation (NIPPV or NHFV)
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias