Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,261 questions · 1,287 findings · 210 reviews

No studies found 256 · 19.9%GRADE not reported 123 · 9.6%Very low 248 · 19.3%Low 403 · 31.3%Moderate 208 · 16.2%High 49 · 3.8%

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Medication given before LTP showed no clear difference in IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with the same medication given after LTP (moderate certainty).

1 finding from 1 review

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication given before LTP changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with the same medication given after LTP (very low certainty).

1 finding from 1 review