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Evidence found and GRADE certainty

127 questions · 135 findings · 22 reviews

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No studies found 33 · 24.4%GRADE not reported 19 · 14.1%Very low 45 · 33.3%Low 23 · 17%Moderate 10 · 7.4%High 5 · 3.7%

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Preterm birth · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in preterm birth compared with same supplement without iodine or no treatment/placebo (maternal… (low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Maternal adverse effect: elevated thyroid peroxidase antibodies ‐ pregnancy · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in maternal adverse effect: elevated thyroid peroxidase antibodies ‐… compared with same supplement without iodine or no treatment/placebo (maternal… (low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Maternal adverse effect: elevated TPO‐ab ‐ postpartum · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in maternal adverse effect: elevated TPO‐ab ‐ postpartum compared with same supplement without iodine or no treatment/placebo (maternal… (low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Maternal adverse effect: hyperthyroidism ‐ pregnancy · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in maternal adverse effect: hyperthyroidism ‐ pregnancy compared with same supplement without iodine or no treatment/placebo (maternal… (low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Maternal adverse effect: hyperthyroidism ‐ postpartum · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in maternal adverse effect: hyperthyroidism ‐ postpartum compared with same supplement without iodine or no treatment/placebo (maternal… (low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Maternal adverse effect: digestive intolerance ‐ pregnancy · women during the preconception, pregnancy and postpartum period

It is very uncertain whether any supplement containing iodine changes maternal adverse effect: digestive intolerance ‐ pregnancy compared with same supplement without iodine or no treatment/placebo (maternal… (very low certainty).

1 finding from 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes)

Perinatal mortality · women during the preconception, pregnancy and postpartum period

Any supplement containing iodine showed no clear difference in perinatal mortality compared with same supplement without iodine or no treatment/placebo (child… (low certainty).

1 finding from 1 review