Cochrane · systematic review · CD005253
Iodine supplementation for the prevention of mortality and adverse neurodevelopmental outcomes in preterm infants
Walsh, V, Brown, JVE, McGuire, W · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 5 · 100%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Iodine supplementation compared to control for the prevention of mortality and adverse neurodevelopmental outcomes in preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality before hospital discharge Iodine supplementation vs control | RR 1.01 [0.72, 1.42] | 2 studies · 1380 participants | High |
Bayley‐III Cognitive composite score at 2 years of age corrected for prematurity Iodine supplementation vs control | no estimate extracted | 1 study · 1259 participants | High |
Bayley‐III Motor composite score at 2 years of age corrected for prematurity Iodine supplementation vs control | no estimate extracted | 1 study · 1259 participants | High |
Bayley‐III Language composite score at 2 years of age corrected for prematurity Iodine supplementation vs control | no estimate extracted | 1 study · 1259 participants | High |
Low score in any main Bayley domain (< 85) or death Iodine supplementation vs control | RR 1.05 [0.94, 1.17] | 1 study · 1259 participants | High |