Question · asked by 1 review

Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (maternal outcomes): Perinatal mortality

Population
women during the preconception, pregnancy and postpartum period
Intervention
Any supplement containing iodine
Comparison
same supplement without iodine or no treatment/placebo (maternal outcomes)
Outcome
Perinatal mortality

Any supplement containing iodine showed no clear difference in perinatal mortality compared with same supplement without iodine or no treatment/placebo (child… (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Any supplement containing iodine vs same supplement without iodine or no treatment/placebo (child outcomes)
Perinatal mortality · women during the preconception, pregnancy and postpartum period
Any supplement containing iodine showed no clear difference in perinatal mortality compared with same supplement without iodine or no treatment/placebo (child… (low certainty).
Iodine supplementation for women during the preconception, pregnancy and postpartum period (2017) · Cochrane Headline outcomes only
RR 0.66 [0.42, 1.03]1 study · 399 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Iodine supplementation for women during the preconception, pregnancy and postpartum period
2017 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.