Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

59 questions · 60 findings · 9 reviews · Eyes and Vision

No studies found 12 · 20%GRADE not reported 2 · 3.3%Very low 10 · 16.7%Low 17 · 28.3%Moderate 16 · 26.7%High 3 · 5%

Intravitreal triamcinolone acetonide injection 4 mg vs antiVEGF

Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · macular edema in diabetes

It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in central retinal thickness (micron) ‐ 12 months (negative… compared with antiVEGF (very low certainty).

1 finding from 1 review

Surgery vs botulinum neurotoxin injections

Treatment success: improvement in the angle of strabismus at 6 months · children with infantile esotropia

It is very uncertain whether surgery changes treatment success: improvement in the angle of strabismus at 6 months compared with botulinum neurotoxin injections (very low certainty).

1 finding from 1 review

Combined steroid and antibiotic therapy vs antibiotics alone

Complete resolution of endophthalmitis at 3 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

It is very uncertain whether combined steroid and antibiotic therapy changes complete resolution of endophthalmitis at 3 months' compared with antibiotics alone (very low certainty).

1 finding from 1 review

Combined steroid and antibiotic therapy vs antibiotics alone

Visual acuity · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

Combined steroid and antibiotic therapy may leads to higher visual acuity 6/6 to 6/18 at 3 months' compared with antibiotics alone (low certainty).

2 findings from 1 review