Emergence agitation—Fentanyl · patients with emergence agitation
Other GA/adjunct leads to lower emergence agitation—Fentanyl compared with sevoflurane anaesthesia (high certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with moderate to severe cancer pain
1 finding from 1 review
Relief of pain · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Nausea · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Vomiting · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Dizziness · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Constipation · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Quality of life · people with moderate to severe cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
Pain (PIPP) · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Duration of mechanical ventilation · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal mortality · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mortality before hospital discharge · neonates with mechanical ventilation
It is very uncertain whether morphine changes mortality to discharge compared with fentanyl (very low certainty).
1 finding from 1 review
Neurodevelopmental outcomes · neonates with mechanical ventilation
The review found no eligible studies for this question.
3 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Additional analgesia required (escape analgesia) · children undergoing surgery
1 finding from 1 review
Proportion of participants with moderate to severe pain up to 6 hours after the procedure · children undergoing surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · children undergoing surgery
1 finding from 1 review
Number requiring opioids postoperatively · patients with postoperative pain
Clonidine showed no clear difference in number requiring opioids postoperatively compared with fentanyl (moderate certainty).
1 finding from 1 review
Single small study · patients with postoperative pain
1 finding from 1 review
no estimate extracted
1 participants
GRADE not reported
Additional analgesia required (escape analgesia) · patients with postoperative pain
Clonidine showed no clear difference in number requiring additional analgesia at any time postoperatively compared with fentanyl (moderate certainty).
1 finding from 1 review
Intervention not reported
Moderate benefit: at least 30% reduction in pain, or PGIC much or very much improved · Adults with chronic neuropathic pain
1 finding from 1 review