Caries prevalence (early childhood caries) · Preschool children aged <=71 months (caries outcome assessed at 3-6 years)
Preschool children exposed to secondary smoking have higher odds of caries prevalence (OR 1.77), but the cross-sectional evidence is very uncertain (very low certainty).
2 findings from 1 review
Early childhood caries (ECC) - incidence/risk · Preschool children aged <=71 months (caries outcome assessed at 3-6 years)
Children exposed to secondary smoking from infancy have a higher incidence of early childhood caries by age 3 (RR 1.45; low certainty).
1 finding from 1 review
Caries in primary teeth: dmft (3 years) · Children and adolescents with epilepsy
The review found no statistically significant difference in dmft among children or adolescents.
1 finding from 1 review
Caries in primary teeth: dmft (3 years) · Children and adolescents with epilepsy
In children/adolescents, the dmft (primary teeth) index does not differ significantly with epilepsy (SMD 0.132, 95% CI -0.220 to 0.484, P = .463; ungraded subgroup).
1 finding from 1 review
Mean DMFT (decayed, missing, filled permanent teeth) · Children and adolescents with epilepsy
In children/adolescents, the higher DMFT with epilepsy is not statistically significant (SMD 0.334, 95% CI -0.140 to 0.827, P = .164; ungraded subgroup).
1 finding from 1 review
Mean DMFT (decayed, missing, filled permanent teeth) · people with epilepsy
People with epilepsy have a significantly higher DMFT (permanent-teeth caries) index than controls (SMD 0.403, 95% CI 0.057 to 0.749; high certainty).
1 finding from 1 review
Mean DMFT (decayed, missing, filled permanent teeth) · Adults with epilepsy
In adults, epilepsy is associated with a significantly higher DMFT than controls (SMD 0.548, P < .001; ungraded subgroup analysis).
1 finding from 1 review
Caries in primary teeth: dmft (3 years) · people with epilepsy
The dmft (primary-teeth caries) index does not differ significantly between people with epilepsy and controls (SMD 0.132, 95% CI -0.22 to 0.484; high certainty).
1 finding from 1 review
Salivary IL-6 level (pg/mL) · Children and young adults (3-25 years)
Salivary IL-6 levels are significantly higher in children and young adults with active dental caries than in caries-free or mild-caries controls (SMD 11.60 pg/mL, 95% CI 6.27 to 16.94; 11 studies); ungraded.
1 finding from 1 review
Salivary IL-8 level (pg/mL) · Children and young adults (3-25 years)
Salivary IL-8 levels are higher in children and young adults with active dental caries than in controls but the difference is not statistically significant (SMD 57.20 pg/mL, 95% CI -18.60 to 133.00; 7 studies); ungraded.
1 finding from 1 review
TNF-α level · Children and young adults (3-25 years)
Salivary TNF-α levels are significantly higher in children and young adults with active dental caries than in caries-free or mild-caries controls (SMD 14.81 pg/mL, 95% CI 4.76 to 24.86; 7 studies); ungraded.
1 finding from 1 review
Food choice · Children and adolescents (general population, aged under 20 years)
In crossover studies with binary outcomes, food marketing had no clear association with food choice (OR 3.45, 95% CI 0.97 to 12.43; ungraded).
1 finding from 1 review
OR 3.45 [0.97, 12.43]
3 studies
GRADE not reported
Food purchasing · Children and adolescents (general population, aged under 20 years)
Across five studies, 40% showed any association of potential public health harm for food purchasing (very low certainty).
1 finding from 1 review
Dental caries · Children and adolescents (general population, aged under 20 years)
Across two studies, 50% showed any association of potential public health harm for dental caries (very low certainty).
1 finding from 1 review
Food preference · Children and adolescents (general population, aged under 20 years)
In crossover studies with binary outcomes, food marketing increased food preference (OR 3.49, 95% CI 2.03 to 6.22; ungraded).
1 finding from 1 review
OR 3.49 [2.03, 6.22]
4 studies
GRADE not reported
Relative abundance of S. mutans in saliva · Individuals assessed for dental caries, predominantly children with early childhood caries (ECC) or severe ECC (age about 1 to 4 years)
A few small studies report Streptococcus mutans relative abundance in caries versus caries-free children without pooling; the evidence is ungraded and not meta-analyzed.
1 finding from 1 review
Relative abundance of Veillonella spp. · Individuals assessed for dental caries, predominantly children with early childhood caries (ECC) or severe ECC (age about 1 to 4 years)
Evidence on whether Veillonella spp. relative abundance is higher or lower in children with dental caries than caries-free controls is inconsistent across 7 small observational studies; no pooled estimate was produced and the evidence is ungraded.
1 finding from 1 review
Food intake · Children and adolescents (general population, aged under 20 years)
Food marketing was associated with a significant increase in children's food intake (pooled SMD, 0.25; combined RCT and nonrandomized evidence).
3 findings from 1 review
Food preference · Children and adolescents (general population, aged under 20 years)
Food marketing was associated with increased food preference (pooled SMD, 0.30; combined evidence).
3 findings from 1 review
Dental caries · Children and adolescents (general population, aged under 20 years)
Evidence on food marketing and dental caries is very uncertain (very low certainty); 1 of 2 studies found an association.
1 finding from 1 review