Immediate treatment probably leads to higher adverse events (control ‐ deferred treatment) compared with controls (moderate certainty).
Immediate treatment may leads to higher adverse events (control ‐ no treatment) compared with controls (low certainty).
Untargeted antifungal treatment with any antifungal drug (systemic… showed no clear difference in adverse events requiring cessation of study drug(s) compared with placebo/no antifungal/any other antifungal (low certainty).
It is very uncertain whether DOPAMINERGIC DRUGS changes acceptability of treatment: Leaving the study early compared with OTHER DRUGS (very low certainty).
Antibiotic treatment showed no clear difference in microbial resistance to prophylactic drug compared with placebo or no treatment (moderate certainty).
The review found no eligible studies for this question.
SCS treatment for 7 or fewer days showed no clear difference in adverse drug effect—hyperglycaemia compared with SCS treatment (moderate certainty).
SCS treatment for 7 or fewer days showed no clear difference in adverse drug effects Gastrointestinal tract bleeding, symptomatic… compared with SCS treatment (low certainty).
Olanzapine showed no clear difference in participant preference ‐ wish to use drug in next treatment compared with placebo/no treatment (moderate certainty).
It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes disability‐worsening Proportion of participants with… compared with placebo? (very low certainty).
It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes relapse Proportion of participants with relapse during 24 months of… compared with placebo? (very low certainty).
Are disease‐modifying drugs for a first attack suggestive of… showed no clear difference in occurrence of at least one serious adverse event Proportion of… compared with placebo? (low certainty).
The intervention showed no clear difference in positive urine drug test (end of treatment) (Any psychosocial… (moderate certainty).
It is very uncertain whether DOPAMINERGIC DRUGS changes acceptability of treatment: Leaving the study early compared with PLACEBO (very low certainty).
It is very uncertain whether NORADRENERGIC DRUGS changes acceptability of treatment: Leaving the study early compared with PLACEBO (very low certainty).
Antiepileptic drugs showed no clear difference in any serious adverse event of treatment count of events compared with placebo or standard care (low certainty).