Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

627 questions · 638 findings · 45 reviews

No studies found 89 · 13.9%GRADE not reported 37 · 5.8%Very low 221 · 34.6%Low 181 · 28.4%Moderate 92 · 14.4%High 18 · 2.8%

Antidepressants vs placebo according to any definition

Dropout ‐ Dropouts: excluding studies with high risk of bias objective · patients with cocaine abuse and dependence

Antidepressants showed no clear difference in dropout ‐ Dropouts: excluding studies with high risk of bias objective compared with placebo according to any definition (moderate certainty).

1 finding from 1 review