Antidepressants vs benzodiazepines: Withdrawals due to adverse events
- Population
- adults with panic disorder
- Intervention
- Antidepressants
- Comparison
- benzodiazepines
- Outcome
- Withdrawals due to adverse events
Antidepressants may leads to higher number of dropouts due to adverse effects compared with benzodiazepines (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antidepressants vs benzodiazepines number of dropouts due to adverse effects · adults with panic disorder Antidepressants may leads to higher number of dropouts due to adverse effects compared with benzodiazepines (low certainty). Antidepressants and benzodiazepines for panic disorder in adults (2016) · Cochrane Headline outcomes only | RR 1.72 [1.03, 2.87] | 3 studies · 1002 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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- Antidepressants vs placebo · adults with panic disorder · 1 review
- Antidepressants vs a combination of medications · somatoform disorders in adults · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.