Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

62 questions · 65 findings · 17 reviews · Stroke

No studies found 15 · 23.1%GRADE not reported 5 · 7.7%Very low 15 · 23.1%Low 11 · 16.9%Moderate 11 · 16.9%High 8 · 12.3%

Percutaneous vascular interventions vs intravenous thrombolytic treatment

Symptomatic intracranial haemorrhage at

Percutaneous vascular interventions showed no clear difference in symptomatic intracranial haemorrhage within first 14 days compared with intravenous thrombolytic treatment (low certainty).

1 finding from 1 review

Low‐molecular‐weight heparins or heparinoids vs unfractionated heparin

Symptomatic intracranial haemorrhage/haemorrhagic transformation of the cerebral infarct during treatment period (range 6 days to 16 days)⁹ · acute ischaemic stroke

Low‐molecular‐weight heparins or heparinoids showed no clear difference in symptomatic intracranial haemorrhage/haemorrhagic transformation of… compared with unfractionated heparin (low certainty).

1 finding from 1 review

Intervention not reported

Quality of life: Stroke Impact Scale (SIS) SIS measures quality of life across five domains: physical (strength, hand‐function, mobility, activities of daily living), emotion, memory, communication, social participation, plus 1 global question abo... · adults with stroke
1 finding from 1 review

Intervention not reported

Quality of life: Stroke‐specific QoL Scale (SS QoL) The Stroke‐specific QoL Scale measures quality of life across 12 domains (49 items): self‐care, vision, language, mobility, work, upper extremity, thinking, personality, mood, family, social, and... · adults with stroke
1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death or stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher death or stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Type of recurrent event · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in type of recurrent event compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment may leads to higher death compared with conventional medical treatment alone (low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Dependency · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in dependency compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review