Cochrane · systematic review · CD013312

Treatments for unruptured intracranial aneurysms

Pontes, FG, da Silva, EMK, Baptista-Silva, JCC, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
7
No studies
9
Included studies
NR
No studies 9 · 56.3%Ungraded 0 · 0%Very low 7 · 43.8%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Microsurgical clipping compared to endovascular coiling for unruptured intracranial aneurysms

Population: people with unruptured intracranial aneurysms
8 questions
OutcomeEffectEvidenceStatus / GRADE
Morbidity (GOS) Short term
Microsurgical clipping vs endovascular coiling
no estimate extracted1 study · 134 participantsVery low
Downgraded: risk of bias, imprecision
Death
Microsurgical clipping vs endovascular coiling
no estimate extracted1 study · 106 participantsVery low
Downgraded: risk of bias, imprecision
Stroke
Microsurgical clipping vs endovascular coiling
no estimate extracted1 study · 104 participantsVery low
Downgraded: risk of bias, imprecision
Infection rate Short term (0 to 30 days)
Microsurgical clipping vs endovascular coiling
no estimate extractedNRNo studies
Infection rate Long term (30 to 365 days)
Microsurgical clipping vs endovascular coiling
no estimate extractedNRNo studies
Blood loss during the procedure
Microsurgical clipping vs endovascular coiling
no estimate extractedNRNo studies
Length of hospital stay
Microsurgical clipping vs endovascular coiling
no estimate extracted1 study · 134 participantsVery low
Downgraded: risk of bias, imprecision
Procedure‐related costs
Microsurgical clipping vs endovascular coiling
no estimate extractedNRNo studies

Conservative treatment compared with endovascular coiling for unruptured intracranial aneurysms

Population: people with unruptured intracranial aneurysms
8 questions
OutcomeEffectEvidenceStatus / GRADE
Morbidity (GOS)
Conservative treatment vs endovascular coiling
no estimate extracted1 study · 80 participantsVery low
Downgraded: risk of bias, imprecision
Death
Conservative treatment vs endovascular coiling
no estimate extracted1 study · 80 participantsVery low
Downgraded: risk of bias, imprecision
Stroke
Conservative treatment vs endovascular coiling
no estimate extracted1 study · 80 participantsVery low
Downgraded: risk of bias, imprecision
Infection rate Short term (0 to 30 days)
Conservative treatment vs endovascular coiling
no estimate extractedNRNo studies
Infection rate Long term (30 to 365 days)
Conservative treatment vs endovascular coiling
no estimate extractedNRNo studies
Blood loss during the procedure
Conservative treatment vs endovascular coiling
no estimate extractedNRNo studies
Length of hospital stay
Conservative treatment vs endovascular coiling
no estimate extractedNRNo studies
Procedure‐related costs
Conservative treatment vs endovascular coiling
no estimate extractedNRNo studies