Oral misoprostol one‐ to two‐hourly vs oral misoprostol four‐ to six‐hourly
- no estimate extracted1 study · 64 participantsVery low
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Oral misoprostol 20 µg hourly titrated showed no clear difference in vaginal birth within 24 hours compared with oral misoprostol 25 µg two‐hourly static (low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes caesarean section compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes oxytocin augmentation compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes apgar score less than 7 at 5 minutes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol 20 µg hourly titrated changes admission to NICU compared with oral misoprostol 25 µg two‐hourly static (very low certainty).
It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with placebo/no treatment (very low certainty).
It is very uncertain whether oral misoprostol changes apgar score less than 7 at 5 minutes compared with placebo/no treatment (very low certainty).
Oral misoprostol showed no clear difference in vaginal birth within 24 hours compared with vaginal dinoprostone (low certainty).
Oral misoprostol probably leads to lower caesarean section compared with vaginal dinoprostone (moderate certainty).
Effect of LF‐LAM probably leads to lower mortality at 8 weeks compared with no LF‐LAM on mortality and tuberculosis treatment initiation (moderate certainty).
Effect of LF‐LAM showed no clear difference in people started on tuberculosis treatment compared with no LF‐LAM on mortality and tuberculosis treatment initiation (moderate certainty).
Effect of LF‐LAM showed no clear difference in mortality at 6 months compared with no LF‐LAM on mortality and tuberculosis treatment initiation (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
The review found no eligible studies for this question.