Findings

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Evidence found and GRADE certainty

4,776 questions · 7,311 findings · 959 reviews · Headline outcomes only

No studies found 1,498 · 20.5%GRADE not reported 303 · 4.1%Very low 1,839 · 25.2%Low 1,991 · 27.2%Moderate 1,277 · 17.5%High 403 · 5.5%

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Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Uterine hyperstimulation with fetal heart rate changes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation with FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Uterine hyperstimulation without fetal heart rate changes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes uterine hyperstimulation without FHR changes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static

Apgar score less than 7 at 5 minutes · induction of labour.

It is very uncertain whether oral misoprostol 20 µg hourly titrated changes apgar score less than 7 at 5 minutes compared with oral misoprostol 25 µg two‐hourly static (very low certainty).

1 finding from 1 review

Oral misoprostol vs placebo/no treatment

Uterine hyperstimulation without fetal heart rate changes · women with ruptured membranes in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Oral misoprostol vs placebo/no treatment

Apgar score less than 7 at 5 minutes · women with ruptured membranes in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes apgar score less than 7 at 5 minutes compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation

Mortality at 8 weeks · adults living with HIV

Effect of LF‐LAM probably leads to lower mortality at 8 weeks compared with no LF‐LAM on mortality and tuberculosis treatment initiation (moderate certainty).

1 finding from 1 review

Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation

People started on tuberculosis treatment · adults living with HIV

Effect of LF‐LAM showed no clear difference in people started on tuberculosis treatment compared with no LF‐LAM on mortality and tuberculosis treatment initiation (moderate certainty).

2 findings from 1 review

Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation

Mortality at 6 months · adults living with HIV

Effect of LF‐LAM showed no clear difference in mortality at 6 months compared with no LF‐LAM on mortality and tuberculosis treatment initiation (low certainty).

1 finding from 1 review