Cochrane · systematic review · CD014641
Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV
Nathavitharana, RR, Lederer, P, Chaplin, M, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Effect of LF‐LAM compared to no LF‐LAM on mortality and tuberculosis treatment initiation in people living with HIV, inpatient settings
Population: adults living with HIV
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality at 8 weeks Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation | RR 0.85 [0.76, 0.94] | 2 studies · 5102 participants | Moderate Downgraded: risk of bias, indirectness |
People started on tuberculosis treatment Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation | RR 1.26 [0.94, 1.69] | 2 studies · 5102 participants | Moderate Downgraded: risk of bias, indirectness |
Effect of LF‐LAM compared to no LF‐LAM on mortality and tuberculosis treatment initiation in people living with HIV, outpatient settings
Population: adults living with HIV
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality at 6 months Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation | RR 0.89 [0.71, 1.11] | 1 study · 2972 participants | Low Downgraded: imprecision, indirectness |
People started on tuberculosis treatment Effect of LF‐LAM vs no LF‐LAM on mortality and tuberculosis treatment initiation | RR 5.44 | 1 study · 3022 participants | Low Downgraded: imprecision, indirectness |